ArticleArchives of dermatological research2024
Efficacy of tranexamic acid solution versus vitamin C solution after micro-needling in treatment of persistent post acne erythema: a split face clinical and 3DAntera camera comparative study.
Article in Archives of dermatological research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Efficacy and Safety of a Dual-Wavelength 589/1319 nm Laser for the Treatment of Acne Erythema: A Split-Face Randomized Controlled Trial.Journal of cosmetic dermatology · 2026Trial
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Post acne erythema (PAE) is a common sequela of acne inflammation, and it refers to telangiectasia and erythematous lesions remaining after the acne treatment. Although some PAE may improve over time, persisting PAE might be esthetically undesirable for patients. The efficacy of various treatment options for PAE has been investigated in many studies but there exists no gold standard treatment modality. This current split face comparative study aimed to assess and compare the therapeutic efficacy of vitamin c solution 10% with microneedling versus Tranexamic acid solution (TXA) (50 mg/ml) with microneedling in treating patients with PAE. Four sessions were held, two weeks apart. The assessment was done 2 weeks after the last session via change in Clinical Erythema Assessment (CEA) score, Antera 3D camera parameter changes (average hemoglobin level and hemoglobin variation), and patient satisfaction scale. Also, side effects were documented. Our study showed that both topical vitamin C and TXA solutions after microneedling showed significant decrease in hemi-CEA score and Antera camera measures of both Hb variations and average Hb levels. However, TXA treated side showed superior improvement than the side treated with vitamin c. Also, there was great patient satisfaction on both treated sides. The side effects reported were transient and minimal. Microneedling with TXA solution is a safe, effective and readily available modality of PAE treatment and showed superior results over vitamin C solution. Antera 3D camera is an excellent objective tool for assessing even minimal changes in Hb level and variation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.