Evidence map›Paper›PMID 39707757›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2025

Association between infant feeding and ADHD development in childhood: a birth cohort study in Taiwan.

Chiu-Ying Chen, Pin-Yang Shih, Chih-Ting Su, Chi-Fung Cheng, Meng-Chih Lee, Hsien-Yuan Lane

Abstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chiu-Ying Chen *Graduate Institute of Clinical Medical Science, College of Medicine, China Medical University, Taichung, Taiwan.ORCID 0000-0001-8454-1151
Pin-Yang Shih *Department of Public Health, China Medical University, Taichung, Taiwan.
Chih-Ting SuOffice of Food and Drug Safety, Health Bureau of Taichung City Government, Taichung, Taiwan.
Chi-Fung ChengNational Center for Geriatrics and Welfare Research, National Health Research Institutes, Miaoli, Taiwan.
Meng-Chih Lee *Department of Family Medicine, Taichung Hospital, Ministry of Health and Welfare, Taichung, Taiwan.ORCID 0000-0003-4650-395X
Hsien-Yuan Lane *Graduate Institute of Clinical Medical Science, College of Medicine, China Medical University, Taichung, Taiwan.ORCID 0000-0003-2162-8174

Funding

China Medical University, Taichung, Taiwan CMU103-TC-02Health Promotion Administration, Ministry of Health and Welfare, Taiwan DOH93-HP-1702
6 · The paper itself

Abstract

backgroundInfant feeding plays a vital role in neurodevelopment, and a lack of breastfeeding and complementary feeding may increase the risk of developing attention-deficit/hyperactivity disorder (ADHD). However, empirical evidence on this relationship remains uncertain, as most studies are based on cross-sectional designs. Therefore, this study aimed to examine this temporal relationship using longitudinal data from a birth cohort.

methodsA retrospective cohort study was conducted using data from Wave I (starting at 6 months old, 2005-2006) to Wave IV (up to 5 years old, 2010-2011) of the Taiwan Birth Cohort Study. A total of 19,721 pairs completed the four-wave interviews and provided information on infant feeding, medical history, ADHD occurrence, and sociodemographic characteristics. An extended Cox model with time-dependent covariates was used to examine this association.

resultsIn total, 207 infants developed ADHD during the 54-month observational period, with an estimated cumulative incidence of 5.56 per 1,000 person-years. The average breastfeeding duration was approximately 2 months. With complementary feeding, rice solid food (HR = 0.73) was found to be a protective factor against developing ADHD. Significantly associated factors for increasing ADHD risk included males, lower family income, low birth weight, maternal weight, advanced maternal age, child gastrointestinal disease, child seizures, maternal heart disease, and paternal diabetes mellitus.

conclusionsComplementary feeding within 6 months is important to protect infants from developing ADHD. The beneficial effect of breastfeeding within 6 months was not observed while controlling for other risk factors. However, owing to the limitation of a smaller number of ADHD cases, further studies should rely on larger observational periods.

Indexed as

Attention Deficit Disorder with HyperactivityBreast FeedingInfant Nutritional Physiological PhenomenaAdultBirth CohortChild, PreschoolFemaleHumansInfantLongitudinal StudiesMaleRetrospective StudiesRisk FactorsTaiwanattention‐deficit/hyperactivity disorderbirth cohortbreastfeedingcomplementary feedingInfant feeding

Identifiers

PMID39707757
PMCPMC12062847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.