ArticleJournal of applied clinical medical physics2025
Automated daily dose accumulation workflow for treatment quality assurance during online adaptive radiotherapy with a 0.35T MR-linac.
Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Impact of intra- and interfractional motion on the dose distribution and urinary adverse events for magnetic resonance-guided prostate cancer radiotherapy.Physics and imaging in radiation oncology · 2026Article
- Automated daily dose accumulation workflow for treatment quality assurance during online adaptive radiotherapy with a 0.35T MR-linac.Journal of applied clinical medical physics · 2025Article
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Authors and funding
7 authors.
Funding
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Abstract
purposeThis study assesses a novel, automated dose accumulation process during MR-guided online adaptive radiotherapy (MRgART) for prostate cancer, focusing on inter-fractional anatomical changes and discrepancies between delivered and planned doses.
methodsA retrospective analysis was conducted on seven prostate cancer patients treated with a five-fraction stereotactic body radiation therapy (SBRT), using a 0.35T MRIdian MR-LINAC system. Daily plans were adapted when dose thresholds were exceeded. Planning MRI (pMRI) and daily MRIs (dMRIs) were imported into MIM software for automated and manual dose accumulation procedures. Rigid and deformable image registrations were followed by dose accumulation to compare delivered and planned doses. Manual and automated image registrations were compared by calculating the Hausdorff distance (HD), Jaccard, and DICE metrics.
resultsModerate discrepancies in dosimetric parameters for the planning target volume (PTV) were observed between auto-accumulated and planned doses, such as
conclusionThe automated workflow, developed in collaboration with MIM Software Inc., demonstrates high accuracy compared to manual accumulation. The moderate differences observed between planned and accumulated doses emphasize the need for accurate dose accumulation for adaptive plans.
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