Evidence map›Paper›PMID 39707503›Full record

ReviewCell communication and signaling : CCS2024

V-ATPase in cancer: mechanistic insights and therapeutic potentials.

Tingting Chen, Xiaotan Lin, Shuo Lu, Bo Li

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell communication and signaling : CCS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Recent progress in small molecules targeting the acidic tumor microenvironment.Journal of enzyme inhibition and medicinal chemistry · 2026
    Review
  3. [ATPase HZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Article
  4. Anoikis: To Die or Not to Die?International journal of molecular sciences · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tingting ChenSchool of Basic Medicine, Guangdong Medical University, DongGuan, China. jkf_ctt@163.com.
Xiaotan LinDepartment of Family Planning, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, Shenzhen, China.
Shuo LuSchool of Basic Medicine, Guangdong Medical University, DongGuan, China.
Bo LiCollege of Basic Medical Science, Jinzhou Medical University, Jinzhou, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vacuolar-type H+-ATPase (V-ATPase) is a crucial proton pump that plays an essential role in maintaining intracellular pH homeostasis and a variety of physiological processes. This review provides an in-depth exploration of the structural components, functional mechanisms, and regulatory modes of V-ATPase in cancer cells. Comprising two main domains, V

Indexed as

NeoplasmsVacuolar Proton-Translocating ATPasesAMP-Activated Protein KinasesAnimalsAutophagyHumansMechanistic Target of Rapamycin Complex 1Tumor MicroenvironmentAMP-Activated Protein KinasesMechanistic Target of Rapamycin Complex 1Vacuolar Proton-Translocating ATPasespH homeostasisProton pumpTherapeutic targetsV-ATPase

Identifiers

PMID39707503
PMCPMC11660900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.