Evidence map›Paper›PMID 39707470›Full record

ArticleJournal of medical case reports2024

Postorgasmic illness syndrome benefiting from omalizumab and antidepressant: a case report.

Kasım Okan, Ragıp Fatih Kural, Meryem Demir, Furkan Cot, Mustafa Dinckal, Sevgi Altay, Nihal Mete Gökmen

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kasım OkanDepartment of Internal Medicine, Division of Allergy and Immunology, Ege University, Izmir, Turkey. kasimokan55@gmail.com.ORCID http://orcid.org/0000-0002-9743-4336
Ragıp Fatih KuralDepartment of Internal Medicine, Division of Allergy and Immunology, Ege University, Izmir, Turkey.
Meryem DemirDepartment of Internal Medicine, Division of Allergy and Immunology, Ege University, Izmir, Turkey.
Furkan CotDepartment of Urology, Ege University, Izmir, Turkey.
Mustafa DinckalDepartment of Urology, Ege University, Izmir, Turkey.
Sevgi AltayDepartment of Internal Medicine, Division of Allergy and Immunology, Ege University, Izmir, Turkey.
Nihal Mete GökmenDepartment of Internal Medicine, Division of Allergy and Immunology, Ege University, Izmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostorgasmic illness syndrome is characterized by flu, rhinitis, conjunctivitis, loss of appetite, muscle weakness, and fatigue after ejaculation, lasting 2-7 days. The multidisciplinary treatment approach, incorporating omalizumab and antidepressants, has rarely been documented in literature. CASE PRESENTATION: In this article, we present the case of a 33-year-old single Turkish male with postorgasmic illness syndrome, characterized by typical clinical symptoms and a positive autologous semen test. Notably, his serum estrogen and progesterone levels were elevated. The patient's Beck anxiety score was 42 points, the depression scale score was 37, and suicidal thoughts. Fresh autologous semen taken at the hospital was diluted with 0.9% saline, and prick and intradermal skin tests were performed.

conclusionThe patient's symptoms improved significantly with the combination of omalizumab and escitalopram. This case not only provides a new perspective on the management of postorgasmic illness syndrome but also highlights the potential roles of allergic, psychiatric, and endocrinological mechanisms in the etiology and treatment of this complex condition.

Indexed as

OmalizumabAdultAnti-Allergic AgentsAntidepressive AgentsCitalopramDrug Therapy, CombinationHumansMaleSyndromeTreatment OutcomeAnti-Allergic AgentsAntidepressive AgentsCitalopramOmalizumabAllergyMale orgasmic disordersPostorgasm illness syndromeSemen

Identifiers

PMID39707470
PMCPMC11662807

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.