Evidence map›Paper›PMID 39707353›Full record

ArticleBMC urology2024

Clinical effectiveness of unilateral single-armed vasoepididymostomy in obstructive azoospermia: a single-center experience.

Yihong Zhou, Jianjun Dong, Chencheng Yao, Liangyu Zhao, Yuhua Huang, Ruhui Tian, Yingbo Dai, Yuxin Tang, Fujun Zhao, Zheng Li and 2 more

Abstract read
In one paragraph

Article in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yihong Zhou *Department of Andrology, the Center for Men's Health, Shanghai General Hospital, Urologic Medical Center, Shanghai Jiao Tong University, Shanghai, 200080, China.
Jianjun Dong *Department of Andrology, the Center for Men's Health, Shanghai General Hospital, Urologic Medical Center, Shanghai Jiao Tong University, Shanghai, 200080, China.
Chencheng YaoDepartment of Andrology, the Center for Men's Health, Shanghai General Hospital, Urologic Medical Center, Shanghai Jiao Tong University, Shanghai, 200080, China.
Liangyu ZhaoDepartment of Urology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
Yuhua HuangDepartment of Andrology, the Center for Men's Health, Shanghai General Hospital, Urologic Medical Center, Shanghai Jiao Tong University, Shanghai, 200080, China.
Ruhui TianDepartment of Andrology, the Center for Men's Health, Shanghai General Hospital, Urologic Medical Center, Shanghai Jiao Tong University, Shanghai, 200080, China.
Yingbo DaiDepartment of Urology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
Yuxin TangDepartment of Urology, the Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, 519000, China.
Fujun ZhaoDepartment of Andrology, the Center for Men's Health, Shanghai General Hospital, Urologic Medical Center, Shanghai Jiao Tong University, Shanghai, 200080, China.
Zheng LiDepartment of Andrology, the Center for Men's Health, Shanghai General Hospital, Urologic Medical Center, Shanghai Jiao Tong University, Shanghai, 200080, China.
Peng LiDepartment of Andrology, the Center for Men's Health, Shanghai General Hospital, Urologic Medical Center, Shanghai Jiao Tong University, Shanghai, 200080, China. fengzhongjiezou@163.com.
Erlei ZhiDepartment of Andrology, the Center for Men's Health, Shanghai General Hospital, Urologic Medical Center, Shanghai Jiao Tong University, Shanghai, 200080, China. zhzzer1985@126.com.

Funding

Clinical Research Innovation Plan of Shanghai General Hospital CTCCR-2021C17National Natural Science Foundation of China 82171586,82001530Shanghai science and technology innovation action plan project 20Y11907600Strategic Priority Research Program of the Chinese Academy of Sciences XDA16020701
6 · The paper itself

Abstract

backgroundVasoepididymostomy (VE) is an important surgical treatment to achieve natural conception for patients with obstructive azoospermia (OA), and only unilateral VE can be performed under certain conditions, such as OA patients with congenital unilateral absence of the vas deferens (CUAVD) and some acquired OA. There is a lack of relevant reports assessing the clinical outcomes of unilateral VE in OA patients with different causes. This study is aimed to describe the clinical features and evaluate treatments and outcomes of unilateral single-armed VE in OA patients.

methodsFrom December 2015 to June 2021, 46 OA patients (including 13 CUAVD-associated OA and 33 acquired OA) underwent unilateral single-armed VE in Shanghai General Hospital (Shanghai, China). Patient information, semen analysis, hormone profiles, and treatment information were collected, and the clinical outcomes were evaluated.

resultsObstruction in distal of unilateral vas deferens (16/46) was the most common cause for OA patients underwent unilateral VE, and CUAVD accounts for 28.4% (13/46). The overall patency rate was 50.0% (23/46), with 38.5% (5/13) for the CUAVD group and 54.5% (18/33) for the acquired group (p > 0.05). The natural pregnancy rates in CUAVD group and acquired group were 20.0% and 33.3%, respectively (p > 0.05).

conclusionsThese findings suggest unilateral single-armed VE can achieve high patency and pregnancy rates in OA patients, whether for CUAVD or acquired OA patients.

Indexed as

AzoospermiaVas DeferensAdultAnastomosis, SurgicalEpididymisHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeUrologic Surgical Procedures, MaleObstructive azoospermiaPatencyPregnancyUnilateral vasoepididymostomy

Identifiers

PMID39707353
PMCPMC11662787

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.