Evidence map›Paper›PMID 39707283›Full record

Trial reportBMC palliative care2024

Effects of timely case conferencing between general practitioners and specialist palliative care services on symptom burden in patients with advanced chronic disease: results of the cluster-randomised controlled KOPAL trial.

Tina Mallon, Josefine Schulze, Nadine Pohontsch, Thomas Asendorf, Jan Weber, Silke Böttcher, Uta Sekanina, Franziska Schade, Nils Schneider, Judith Dams and 6 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC palliative care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Tina Mallon *Department of General Practice and Primary Care, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0001-5849-6377
Josefine Schulze *Department of General Practice and Primary Care, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany. j.schulze@uke.de.ORCID http://orcid.org/0000-0002-5727-9343
Nadine PohontschDepartment of General Practice and Primary Care, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0002-0966-4087
Thomas AsendorfDepartment of Medical Statistics, University Medical Center Göttingen, Humboldtallee 32, 37073, Göttingen, Germany.ORCID http://orcid.org/0000-0003-1317-2138
Jan WeberInstitute for General Practice and Palliative Care, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.ORCID http://orcid.org/0000-0001-5563-368X
Silke BöttcherDivision of General Practice, Carl von Ossietzky University of Oldenburg, Ammerländer Heerstr. 114-118, 26129, Oldenburg, Germany.ORCID http://orcid.org/0000-0001-5807-7404
Uta SekaninaDepartment of General Practice, University Medical Center Göttingen, Humboldtallee 38, 37073, Göttingen, Germany.ORCID http://orcid.org/0000-0001-5252-5843
Franziska SchadeInstitute for General Practice and Palliative Care, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.ORCID http://orcid.org/0000-0003-3158-4259
Nils SchneiderInstitute for General Practice and Palliative Care, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.ORCID http://orcid.org/0000-0003-3058-5954
Judith DamsDepartment of Health Economics and Health Care Research, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0002-6922-434X
Michael FreitagDivision of General Practice, Carl von Ossietzky University of Oldenburg, Ammerländer Heerstr. 114-118, 26129, Oldenburg, Germany.
Christiane MüllerDepartment of General Practice, University Medical Center Göttingen, Humboldtallee 38, 37073, Göttingen, Germany.ORCID http://orcid.org/0000-0002-7871-0884
Friedemann NauckDepartment of Palliative Medicine, University Medical Center Göttingen, Von-Siebold-Str. 3, 37075, Göttingen, Germany.ORCID http://orcid.org/0000-0001-7592-1654
Tim FriedeDepartment of Medical Statistics, University Medical Center Göttingen, Humboldtallee 32, 37073, Göttingen, Germany.ORCID http://orcid.org/0000-0001-5347-7441
Martin SchererDepartment of General Practice and Primary Care, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.
Gabriella MarxDepartment of General Practice and Primary Care, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0001-6807-9518

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with advanced chronic non-malignant conditions often experience significant symptom burden. Therefore, overcoming barriers to interprofessional collaboration between general practitioners (GPs) and specialist palliative home care (SPHC) teams is essential to facilitate the timely integration of palliative care elements. The KOPAL trial aimed to examine the impact of case conferences between GPs and SPHC teams on symptom burden and pain in patients with advanced chronic heart failure, chronic obstructive pulmonary disease, and dementia.

methodsThe cluster-randomised controlled trial compared a structured palliative care nurse visit followed by an interprofessional case conference to usual care. Data were collected from GPs at baseline and 48 weeks, while standardised patient interviews were conducted at baseline, 6, 12, 24, and 48 weeks.

resultsWe analysed 172 patients from 49 German GP practices. Both groups showed marginal improvement in symptom burden; however, no statistically significant between-group difference was found ([Formula: see text]=-0.561, 95% CI: -3.201-2.079, p = .68). Patients with dementia experienced a significant pain reduction ([Formula: see text]=2.187, 95% CI: 0.563-3.812, p = .009). Conversely, the intervention did not have a significant effect on pain severity ([Formula: see text]=-0.711, 95% CI: -1.430 - 0.008, p=.053) or pain interference ([Formula: see text]=-0.036, 95% CI:-0.797 - 0.725, p=.926) in other patient groups.

conclusionsThe intervention showed promise in the timely introduction of palliative care elements to address pain management in patients with dementia. Further studies are needed to identify and effectively address symptom burden and pain in other patient groups.

trial registrationGerman Clinical Trials Register: https://www.drks.de/DRKS00017795 (Registration date: 9th January 2020).

Indexed as

General PractitionersPalliative CareAgedAged, 80 and overChronic DiseaseCluster AnalysisDementiaFemaleGermanyHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveSymptom BurdenChronic DiseaseCOPDDementiaFamily PracticeHeart FailurePainPalliative CarePrimary Health Care

Identifiers

PMID39707283
PMCPMC11662516

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.