Evidence map›Paper›PMID 39707254›Full record

SynthesisBMC public health2024

The asymptomatic tuberculosis proportion among the elderly population: a systematic review and meta-analysis.

Yiqing Zhou, Fei Wang, Songhua Chen, Yu Zhang, Wei Wang, Qian Wu, Dan Luo, Yuxiao Ling, Yang Li, Luyu Wang and 4 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yiqing Zhou *School of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Fei Wang *Department of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Songhua ChenDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Yu ZhangDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Wei WangDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Qian WuDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.
Dan LuoSchool of Public Health, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Yuxiao LingSchool of Public Health, Health Science Center, Ningbo University, Ningbo, Zhejiang, China.
Yang LiSchool of Public Health, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Luyu WangSchool of Urban Design, Wuhan University, Wuhan, Hubei, China.
Jingru WeiNational Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Bin ChenDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China. bchen@cdc.zj.cn.
Canyou ZhangNational Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. zhangcy@chinacdc.cn.
Kui LiuDepartment of Tuberculosis Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China. kliu@cdc.zj.cn.

Funding

Gates Foundation INV-035022
6 · The paper itself

Abstract

backgroundThe elderly population is a high-risk group for tuberculosis, and increasing evidence demonstrates a comparatively high proportion of asymptomatic tuberculosis in this group. This study aimed to determine the proportion of asymptomatic tuberculosis among patients with active tuberculosis through active case finding in the elderly population. MATERIALS AND

methodsWe searched for relevant articles published from the establishment of each database to December 31, 2023 in Web of Science, PubMed, VIP database, Chinese National Knowledge Infrastructure, and Wanfang database. The studies' quality was assessed using the Agency for Healthcare Research and Quality's criteria. We used the I² statistic and Q test to evaluate heterogeneity across the included studies. We employed subgroup analysis, sensitivity analysis, and meta-regression to pinpoint sources of heterogeneity. Moreover, Begg's and Egger's tests were employed to detect any potential publication biases.

resultsNine studies involving 364,260 elderly individuals met the criteria for the analysis. In active case finding, the proportion of asymptomatic tuberculosis in the elderly population was 67.7% (95% CI: 54.7-79.5%, I

conclusionsThe latest results revealed a significantly high percentage of elderly individuals with asymptomatic tuberculosis. This study highlighted the importance of mass screening to identify active tuberculosis cases in this specific group which could help health policymakers develop better strategies to reduce the burden of tuberculosis in the elderly population.

Indexed as

Asymptomatic InfectionsTuberculosisAgedAged, 80 and overHumansActive case findingActive tuberculosisAsymptomatic tuberculosisElderly

Identifiers

PMID39707254
PMCPMC11662735

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.