Evidence map›Paper›PMID 39707206›Full record

ArticleBMC immunology2024

Comparison of novel native probiotics and paraprobiotics in modulating oxidative stress and inflammation in DSS-induced colitis: implications for enhanced therapeutic strategies in high fat diet.

Niloofar Rezaie, Shadi Aghamohammad, Elham Haj Agha Gholizadeh Khiavi, Mohammad Reza Pourshafie, Malihe Talebi, Mahdi Rohani

Abstract readComparative Study
In one paragraph

Article in BMC immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Paraprobiotics Derived FromFood science & nutrition · 2026
    Article
  2. Preventive effect of heat-killed Lactiplantibacillus plantarum FM8 in an ovalbumin-induced food allergy murine model.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Preventive Effect of ProbioticAntioxidants (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Niloofar Rezaie *Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
Shadi Aghamohammad *Department of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
Elham Haj Agha Gholizadeh KhiaviDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
Mohammad Reza PourshafieDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
Malihe TalebiDepartment of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mahdi RohaniDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran. m_rohani@pasteur.ac.ir.

Funding

Pasteur Institute of Iran B-9740
6 · The paper itself

Abstract

aimIBD is a condition that may result from the presence of oxidative stress. The objective of this research is to evaluate and compare the potency of probiotics and paraprobiotics to modulate oxidative stress and inflammation. METHODS AND

resultsIn the initial phase, the antioxidant capabilities of 88 strains from Lactobacillus and Bifidobacterium were evaluated. In the subsequent phase, during the in-vivo stage, four experimental groups were established, consisting of a high-fat diet (HFD) + PBS, HFD + DSS, HFD + DSS + 10^

conclusionThe study's findings provide evidence that the expression of inflammation can be successfully alleviated by utilizing our native probiotics and paraprobiotics, with a greater emphasis on the latter due to its inherent safety. IMPACT STATEMENTS: This study highlighted the anti-inflammatory and antioxidant properties of probiotic and paraprobiotic that could be useful for patients with inflammatory status.

Indexed as

ColitisDextran SulfateDiet, High-FatInflammationMice, Inbred C57BLOxidative StressProbioticsAnimalsAntioxidantsBifidobacteriumCytokinesDisease Models, AnimalLactobacillusMaleMiceNF-E2-Related Factor 2AntioxidantsCytokinesDextran SulfateNF-E2-Related Factor 2NF-kappa BIBDInflammationOxidative stressParaprobioticProbiotic

Identifiers

PMID39707206
PMCPMC11662435

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.