Evidence map›Paper›PMID 39707164›Full record

ReviewNutrition reviews2025

Adherence and Retention in Early or Late Time-Restricted Eating: A Narrative Review of Randomized Controlled Trials.

Yi Lin, Armin Ezzati, Christian McLaren, Rola S Zeidan, Stephen D Anton

Abstract readReview
In one paragraph

Review in Nutrition reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yi LinDivision of Gerontology, Geriatrics, and Palliative Care, Department of Medicine, College of Medicine, University of Alabama at Birmingham, Birmingham, AL 35233, United States.ORCID 0000-0002-8794-8886
Armin EzzatiDepartment of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, United States.
Christian McLarenDepartment of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, United States.
Rola S ZeidanDepartment of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, United States.
Stephen D AntonDepartment of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, United States.

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
Research Training in Non-Pharmacological Interventions for Cognition in Aging, MCI, and Alzheimer's DiseaseT32AG020499 · NIA · UNIVERSITY OF FLORIDA · PI MARSISKE, MICHAEL, SMITH, GLENN E. · 2003 to 2024
$3.7M
Translational Research Training on Aging and Mobility (TRAM)T32AG062728 · NIA · UNIVERSITY OF FLORIDA · PI Todd Manini · 2020 to 2026
$2.0M
NIA NIH HHS T32 AG020499NIA NIH HHS T32 AG062728NIDDK NIH HHS P30 DK056336
6 · The paper itself

Abstract

Time-restricted eating (TRE) is a form of intermittent fasting that involves reducing the time-period in which food is typically consumed daily. While TRE is known to induce health benefits, particularly for adults with obesity, there is currently debate about whether the time of day in which food is consumed also contributes to the health benefits of TRE. Early TRE (eTRE) and late TRE (lTRE) are subtypes of TRE that involve consuming food and caloric beverages either in the early or later part of the day. A growing body of literature indicates that eTRE may offer additional health benefits compared with lTRE. An important and unanswered question, however, is whether most adults can adhere to this type of eating pattern and whether adherence and retention differ between eTRE and lTRE. This narrative review compared adherence and retention in studies that implemented either eTRE or lTRE in adults for 8 weeks or longer. Five databases were searched, and 10 studies met our eligibility criteria. The key finding was that participants had high and comparable levels of adherence and retention in both eTRE and lTRE interventions. Specifically, the mean adherence rate was 81.4% for eTRE and 82.3% for lTRE, while the mean retention rate was 81% for eTRE and 85.8% for lTRE in eligible studies. Thus, the findings support the feasibility of both approaches. The lowest adherence and retention rates occurred in studies in which either eTRE or lTRE regimens were combined with other dietary interventions. Notably, the duration of the eating window did not seem to negatively affect adherence and retention rates for either eTRE or lTRE. More research is warranted to determine the influence of other factors, such as age and study location, on adherence to and retention of both eTRE and lTRE interventions.

Indexed as

FastingFeeding BehaviorPatient ComplianceAdultHumansRandomized Controlled Trials as TopicTime Factorsadherenceearly time-restricted eatingeating windowintermittent fastinglate time-restricted eatingretention

Identifiers

PMID39707164
PMCPMC12166172

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.