Evidence map›Paper›PMID 39707004›Full record

SynthesisLeukemia2025

Genetic susceptibility of diffuse large B-cell lymphoma: a meta genome-wide association study in Asian population.

Qian Cui, Wen Tan, Bao Song, Rou-Jun Peng, Ling Wang, Rajkumar Dorajoo, Kok Pin Ng, Guo-Wang Lin, Wing-Yan Au, Raymond H S Liang and 17 more

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Leukemia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Qian CuiGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, Guangdong, China.
Wen TanDepartment of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Bao SongShandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Rou-Jun PengState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Ling WangGenome Institute of Singapore, Agency for Science, Technology and Research, A*STAR, 60 Biopolis Street, Singapore, 138672, Singapore.
Rajkumar DorajooGenome Institute of Singapore, Agency for Science, Technology and Research, A*STAR, 60 Biopolis Street, Singapore, 138672, Singapore.ORCID 0000-0001-6608-2051
Kok Pin NgGenome Institute of Singapore, Agency for Science, Technology and Research, A*STAR, 60 Biopolis Street, Singapore, 138672, Singapore.
Guo-Wang LinDepartment of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, Guangdong, China.
Wing-Yan AuBlood-Med Clinic, Central, Hong Kong SAR, China.
Raymond H S LiangHong Kong Sanatorium and Hospital, Hong Kong SAR, China.
Chiea Chuen KhorGenome Institute of Singapore, Agency for Science, Technology and Research, A*STAR, 60 Biopolis Street, Singapore, 138672, Singapore.ORCID 0000-0002-1128-4729
Qing-Ling ZhangGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, Guangdong, China.ORCID 0000-0002-5287-264X
Jia Nee FooGenome Institute of Singapore, Agency for Science, Technology and Research, A*STAR, 60 Biopolis Street, Singapore, 138672, Singapore.ORCID 0000-0001-9899-2308
Sheng-Ping LiState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Fu-Ren ZhangShandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, 27397 Jingshi Road, Jinan, 250022, Shandong, China.
Xue-Jun ZhangDepartment of Dermatology, The First Affiliated Hospital of Anhui Medical University, Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, Hefei, 230032, Anhui, China.
Xue-Qing YuGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, Guangdong, China.
Qing LanDivision of Cancer Epidemiology and Genetics, NCI, Rockville, MD, USA.
Stephen ChanockDivision of Cancer Epidemiology and Genetics, NCI, Rockville, MD, USA.ORCID 0000-0002-2324-3393
Wei-Hua JiaState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Soon Thye LimDivision of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.ORCID 0000-0002-0366-5505
Wen-Yu LiGuangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, Guangdong, China.
Nathaniel Rothman *Division of Cancer Epidemiology and Genetics, NCI, Rockville, MD, USA.
Jin-Xin Bei *State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, China.ORCID 0000-0003-1333-407X
Jie Liu *Shandong Public Health Clinical Center, Shandong University, Shandong, 250013, China.
Dongxin Lin *Department of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jian-Jun Liu *Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, Guangdong, China. liuj3@gis.a-star.edu.sg.ORCID 0000-0002-3255-3019

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy and the most common form of non-Hodgkin lymphoma (NHL) that occurs worldwide. To discover risk factors and pathogenesis of DLBCL, we performed the largest GWAS of DLBCL to date in samples of East Asian ancestry, consisting of 2,888 patients with DLBCL and 12,458 controls. The meta-analysis identified three novel loci, rs2233434 on 6p21.1 (OR = 1.26, P = 1.17 × 10

Indexed as

Asian PeopleGenetic Predisposition to DiseaseGenome-Wide Association StudyLymphoma, Large B-Cell, DiffuseCase-Control StudiesFemaleHumansMalePolymorphism, Single NucleotideQuantitative Trait Loci

Identifiers

PMID39707004

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.