Evidence map›Paper›PMID 39706848›Full record

ArticleScientific reports2024

Epidemiological landscape of tongue cancer in younger patients in a National Cancer Center in Brazil.

Ana Carolina da Silva Souto, Beatriz Nascimento Monteiro da Silva, Fernanda Vieira Heimlich, Otávio Augusto Brioschi Soares, Fernando Luiz Dias, Luiz Henrique de Lima Araujo, Andreia Cristina de Melo, Héliton Spindola Antunes, Luiz Claudio Santos Thuler, Daniel Cohen Goldemberg

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Heterogeneity in Survival Over Time by Age, Sex, and Subsite in Early-Onset Oral Cavity Cancer.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ana Carolina da Silva Souto *Army Health Service Research Center, Army Central Hospital, Rio de Janeiro, Brazil.ORCID 0000-0002-2438-5860
Beatriz Nascimento Monteiro da Silva *Division of Clinical Research, Technological Development of the National Cancer Institute, Rio de Janeiro, Brazil.ORCID 0000-0001-6850-297X
Fernanda Vieira HeimlichSão Lucas University Center, São Paulo, Brazil.ORCID 0000-0001-6933-3450
Otávio Augusto Brioschi SoaresArmy Health Service Research Center, Army Central Hospital, Rio de Janeiro, Brazil.ORCID 0000-0001-9950-912X
Fernando Luiz DiasHead and Neck Surgery Service, National Cancer Institute, Rio de Janeiro, Brazil.ORCID 0000-0003-1000-7436
Luiz Henrique de Lima AraujoDivision of Clinical Research, Technological Development of the National Cancer Institute, Rio de Janeiro, Brazil.
Andreia Cristina de MeloDivision of Clinical Research, Technological Development of the National Cancer Institute, Rio de Janeiro, Brazil.ORCID 0000-0002-1201-4333
Héliton Spindola AntunesDivision of Clinical Research, Technological Development of the National Cancer Institute, Rio de Janeiro, Brazil.ORCID 0000-0002-1076-8019
Luiz Claudio Santos ThulerDivision of Clinical Research, Technological Development of the National Cancer Institute, Rio de Janeiro, Brazil.ORCID 0000-0003-2550-6537
Daniel Cohen GoldembergDivision of Clinical Research, Technological Development of the National Cancer Institute, Rio de Janeiro, Brazil. daniel.cohen@inca.gov.br.ORCID 0000-0002-0089-1910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the changing epidemiological profile of tongue squamous cell carcinoma (SCC) to young patients, highlighting its rising incidence among non-traditional risk groups. A retrospective descriptive study was conducted, covering data from medical records between 2000 and 2012. Patients were categorised into two age groups (≤ 40 years; 41-50 years). Sociodemographic and clinicopathological characteristics were evaluated. A total of 108 patients participated, mostly aged 41-50. Alcohol consumption (43.3%) surpassed smoking. Majority (56.7%) aged ≤ 40 never smoked. Lateral tongue border was most affected, with stages III and IV prevalent. Patients aged ≤ 40 were mostly eligible for surgery (44%). Survival tied to staging and surgery; age had no significant impact. Young squamous cell carcinoma patients often lacked traditional risk factors like smoking, underwent surgery, and typically had disease-free margins. The study underscores the importance of broad external policies for early diagnosis, beyond just traditional risk groups.

Indexed as

Carcinoma, Squamous CellTongue NeoplasmsAdultAge FactorsAlcohol DrinkingBrazilFemaleHumansIncidenceMaleMiddle AgedNeoplasm StagingRetrospective StudiesRisk FactorsSmokingOral cancerOral squamous cell carcinomaSurvivalTongue cancerYoung patients

Identifiers

PMID39706848
PMCPMC11662013

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.