Evidence map›Paper›PMID 39706256›Full record

ArticleThe Journal of investigative dermatology2025

Genetic Analysis of Epidermal Inclusion Cysts Reveals NEK9 Variants as a Common Driver of Comedogenesis and Cyst Formation.

Katharine T Ellis, Peggy Myung, Jeffrey Cohen, Keith A Choate

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katharine T EllisDepartment of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA.
Peggy MyungDepartment of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA; Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA; Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut, USA; Yale Stem Cell Center, Yale University School of Medicine, New Haven, Connecticut, USA.
Jeffrey CohenDepartment of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Biomedical Informatics and Data Science, Yale University School of Medicine, Connecticut, USA.
Keith A ChoateDepartment of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA. Electronic address: keith.choate@yale.edu.

Funding

Medical Scientist Training ProgramT32GM136651 · NIGMS · YALE UNIVERSITY · PI BARBARA I KAZMIERCZAK · 2020 to 2026
$16.5M
Genetics and Pathobiology of Cutaneous Mosaic DisordersR01AR071491 · NIAMS · YALE UNIVERSITY · PI KEITH A CHOATE · 2018 to 2026
$4.2M
Delineating spatiotemporal dynamics of hair follicle dermal niche specification at the single-cell levelR01AR076420 · NIAMS · YALE UNIVERSITY · PI MYUNG, PEGGY S · 2020 to 2024
$1.8M
High Performance Computing Instrumentation for the Yale Center for Genome AnalysisS10OD030363 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2022 to 2022
$1.2M
Leveraging mosaic genodermatoses to discover genetic and molecular mechanisms of comedogenesisF31AR082696 · NIAMS · YALE UNIVERSITY · PI Katharine Taylor Ellis · 2024 to 2026
$104k
NIAMS NIH HHS F31 AR082696NIAMS NIH HHS R01 AR071491NIAMS NIH HHS R01 AR076420NIGMS NIH HHS T32 GM136651NIH HHS S10 OD030363
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BlackheadComedoneEpidermoid cystKeratinocyte differentiationSomatic mosaicism

Identifiers

PMID39706256
PMCPMC12103287

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.