Evidence map›Paper›PMID 39705889›Full record

ArticleComputerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society2025

Portable head CT motion artifact correction via diffusion-based generative model.

Zhennong Chen, Siyeop Yoon, Quirin Strotzer, Rehab Naeem Khalid, Matthew Tivnan, Quanzheng Li, Rajiv Gupta, Dufan Wu

Abstract read
In one paragraph

Article in Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhennong ChenCenter for Advanced Medical Computing and Analysis, Massachusetts General Hospital and Harvard Medical School, Boston, United States.
Siyeop YoonCenter for Advanced Medical Computing and Analysis, Massachusetts General Hospital and Harvard Medical School, Boston, United States.
Quirin StrotzerDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, United States.
Rehab Naeem KhalidDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, United States.
Matthew TivnanCenter for Advanced Medical Computing and Analysis, Massachusetts General Hospital and Harvard Medical School, Boston, United States.
Quanzheng LiCenter for Advanced Medical Computing and Analysis, Massachusetts General Hospital and Harvard Medical School, Boston, United States.
Rajiv GuptaDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, United States.
Dufan WuCenter for Advanced Medical Computing and Analysis, Massachusetts General Hospital and Harvard Medical School, Boston, United States. Electronic address: dwu6@mgh.harvard.edu.

Funding

Optimizing Mobile Photon-Counting CT Image Quality via Deep Learning for Neuro Intensive Care UnitR01EB035394 · NIBIB · OHIO STATE UNIVERSITY · PI Rajiv Gupta, Dufan Wu · 2024 to 2026
$1.3M
Dual Energy CT-enabled Asymptomatic Pulmonary Embolism Detection on Non-contrast CTR21EB031939 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI WU, DUFAN · 2021 to 2021
$449k
NIBIB NIH HHS R01 EB035394NIBIB NIH HHS R21 EB031939
6 · The paper itself

Abstract

Portable head CT images often suffer motion artifacts due to the prolonged scanning time and critically ill patients who are unable to hold still. Image-domain motion correction is attractive for this application as it does not require CT projection data. This paper describes and evaluates a generative model based on conditional diffusion to correct motion artifacts in portable head CT scans. This model was trained to find the motion-free CT image conditioned on the paired motion-corrupted image. Our method utilizes histogram equalization to resolve the intensity range discrepancy of skull and brain tissue and an advanced Elucidated Diffusion Model (EDM) framework for faster sampling and better motion correction performance. Our EDM framework is superior in correcting artifacts in the brain tissue region and across the entire image compared to CNN-based methods and standard diffusion approach (DDPM) in a simulation study and a phantom study with known motion-free ground truth. Furthermore, we conducted a reader study on real-world portable CT scans to demonstrate improvement of image quality using our method.

Indexed as

ArtifactsPhantoms, ImagingTomography, X-Ray ComputedBrainDiffusionHeadHumansImage Processing, Computer-AssistedMotionDiffusion ModelMotion CorrectionPortable Head CT

Identifiers

PMID39705889
PMCPMC11710989

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.