Evidence map›Paper›PMID 39705818›Full record

ArticleDrug and alcohol dependence2025

A wearable alcohol biosensor: Exploring the accuracy of transdermal drinking detection.

Catharine E Fairbairn, Jiaxu Han, Eddie P Caumiant, Aaron S Benjamin, Nigel Bosch

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Applying Artificial Intelligence to Expand the Measurement Tool Kit in Clinical-Psychological Science: Moving Beyond Self-Reports.Clinical psychological science : a journal of the Association for Psychological Science · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Catharine E FairbairnDepartment of Psychology, University of Illinois Urbana-Champaign, Champaign, IL 61820, USA. Electronic address: cfairbai@illinois.edu.
Jiaxu HanDepartment of Psychology, University of Illinois Urbana-Champaign, Champaign, IL 61820, USA.
Eddie P CaumiantDepartment of Psychology, University of Illinois Urbana-Champaign, Champaign, IL 61820, USA.
Aaron S BenjaminDepartment of Psychology, University of Illinois Urbana-Champaign, Champaign, IL 61820, USA.
Nigel BoschSchool of Information Sciences, University of Illinois Urbana-Champaign, Champaign, IL 61820, USA; Department of Educational Psychology, University of Illinois Urbana-Champaign, Champaign, IL 61820, USA.

Funding

Examining the Impact of Stress on the Emotionally Reinforcing Properties of Alcohol in Heavy Social Drinkers: A Multimodal Investigation Integrating Laboratory and Ambulatory MethodsR01AA025969 · NIAAA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Catharine Fairbairn · 2017 to 2026
$3.5M
Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates from New-Generation Transdermal Technology using Large-Scale Human Testing and Machine Learning AlgorithmsR01AA028488 · NIAAA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Catharine Fairbairn · 2021 to 2026
$2.8M
Examining the Neural Correlates of Alcohol Reward in Social Context: A Hyperscanning EEG StudyF31AA031614 · NIAAA · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Jiaxu Han · 2024 to 2026
$149k
NIAAA NIH HHS F31 AA031614NIAAA NIH HHS R01 AA025969NIAAA NIH HHS R01 AA028488
6 · The paper itself

Abstract

backgroundTrace amounts of consumed alcohol are detectable within sweat and insensible perspiration. However, the relationship between ingested and transdermally emitted alcohol is complex, varying across environmental conditions and involving a degree of lag. As such, the feasibility of real-time drinking detection across diverse environments has been unclear. In the current research we revisit sensor performance using new tools, exploring the accuracy of a new generation of rapid-sampling transdermal biosensor for contemporaneous drinking detection across diverse environments via machine learning.

methodsRegular drinkers (N = 100) attended three laboratory sessions involving the experimental manipulation of alcohol dose, rate of consumption, and environmental dosing conditions. Participants further supplied breath alcohol concentration (BAC) readings in the field over 14 days. Participants wore compact wrist sensors capable of rapid sampling (20sec intervals). Transdermal sensor data was translated into alcohol use estimates using machine learning, integrating only transdermal data collected prior to the point of BAC assessment.

resultsA total of 5.39 million transdermal readings (28,615hours) and 12,699 BAC readings were collected for this research. Models indicated strong transdermal sensor accuracy for real-time drinking detection across both laboratory and field contexts (AUROC, 0.966, 95 % CI, 0.956-0.972; Sensitivity, 89.8 %; Specificity, 90.6 %). Models aimed at differentiating high-risk (≥0.08 %) drinking levels yielded intermediate (AUROC, 0.738; 95 % CI, 0.698-0.777; only drinking episodes) to strong (AUROC, 0.941, 95 % CI, 0.929-0.954; all data) accuracy levels.

conclusionsResults indicate a range of useful future applications for transdermal alcohol sensors including long-term health tracking, medical monitoring, and just-in-time relapse prevention.

Indexed as

Alcohol DrinkingBiosensing TechniquesBreath TestsEthanolWearable Electronic DevicesAdolescentAdultFemaleHumansMachine LearningMaleYoung AdultEthanolAlcoholBiosensorSubstance useTransdermalWearables

Identifiers

PMID39705818
PMCPMC11787854

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.