Evidence map›Paper›PMID 39705747›Full record

ArticleThe journal of nutrition, health & aging2025

Prognostic value of nutritional changes in older patients following transcatheter aortic valve replacement.

Hongde Li, Weiya Li, Junli Li, Shiqin Peng, Yuan Feng, Yong Peng, Jiafu Wei, Zhengang Zhao, Tianyuan Xiong, Fei Chen and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of nutrition, health & aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hongde LiDepartment of Cardiology, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, China; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.
Weiya LiDepartment of Cardiology, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, China; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.
Junli LiLaboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.
Shiqin PengDepartment of Cardiology, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, China; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.
Yuan FengDepartment of Cardiology, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, China.
Yong PengDepartment of Cardiology, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, China.
Jiafu WeiDepartment of Cardiology, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, China.
Zhengang ZhaoDepartment of Cardiology, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, China; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.
Tianyuan XiongDepartment of Cardiology, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, China; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.
Fei ChenDepartment of Cardiology, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, China; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China.
Mao ChenDepartment of Cardiology, West China Hospital, Sichuan University, #37 Guoxue Alley, Chengdu, 610041, China; Laboratory of Cardiac Structure and Function, Institute of Cardiovascular Diseases, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address: chenmao@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesNutritional status, as one of the core characteristics of frailty, the impact of its changes on clinical outcomes in older patients following transcatheter aortic valve replacement (TAVR) remains unclear.

designA retrospective cohort study.

settingThis study included a total of 781 patients who underwent TAVR at West China Hospital between 2012 and 2022.

methodThe average age of the patients was 72.6 years, with a mean follow-up period of 2.2 years. All patients were followed for at least one year, and their nutritional status was assessed using the Controlling Nutritional Status (CONUT) score both before TAVR and six months post-TAVR. Based on post-TAVR changes in nutritional status, patients with normal nutritional status pre-TAVR were categorized into Non-malnutrition and New malnutrition groups, while patients with malnutrition pre-TAVR were categorized into Malnutrition regression and Malnutrition persistence groups.

resultThe New malnutrition group experienced higher cumulative incidences of all-cause mortality (20.5% vs. 2.4%, P = 0.002), MACE (25.5% vs. 23.7%, P = 0.001), and readmissions for heart failure (13.1% vs. 7.3%, P = 0.027) compared to the Non-malnutrition group. Conversely, the Malnutrition regression group showed a lower cumulative incidence of all-cause mortality (3.1% vs. 18.0%, P = 0.016) compared to the Malnutrition persistence group, although no statistically significant differences were observed in MACE (14.7% vs. 28.5%, P = 0.087) and readmissions for heart failure (7.0% vs. 8.3%, P = 0.551).

conclusionOur study indicates that deterioration in nutritional status after TAVR is associated with poorer clinical outcomes, whereas improvement is associated with better outcomes.

Indexed as

Aortic Valve StenosisMalnutritionNutritional StatusPostoperative ComplicationsTranscatheter Aortic Valve ReplacementAgedAged, 80 and overChinaFemaleGeriatric AssessmentHeart FailureHumansMaleNutrition AssessmentPatient ReadmissionPrognosisFrailtyMalnutritionNutrition statusTranscatheter aortic valve replacement

Identifiers

PMID39705747
PMCPMC12180016

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.