Evidence map›Paper›PMID 39705587›Full record

ReviewThe journal of extra-corporeal technology2024

Failure to oxygenate during cardiopulmonary bypass; treatment options and intervention algorithm.

Gregory S Matte, William L Regan, Sarah I Gadille, Kevin R Connor, Sharon L Boyle, Francis E Fynn-Thompson

Abstract readReview
In one paragraph

Review in The journal of extra-corporeal technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. National Heart Center Perfusion Guidelines.Saudi medical journal · 2026
    Guideline
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gregory S MatteDepartment of Cardiac Surgery, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
William L ReganDepartment of Cardiac Surgery, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
Sarah I GadilleDepartment of Cardiac Surgery, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
Kevin R ConnorDepartment of Cardiac Surgery, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
Sharon L BoyleDepartment of Cardiac Surgery, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
Francis E Fynn-ThompsonDepartment of Cardiac Surgery, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membrane oxygenator failure remains a concern for perfusion teams. Successful outcomes for this low-frequency, high-risk intervention are predicated on having written institutional protocols for both the oxygenator change-out procedure as well as how often the procedure is practiced by staff perfusionists. A recent review of peer-reviewed journal articles, textbooks and online resources revealed a lack of a unified intervention algorithm for failure to oxygenate during cardiopulmonary bypass (CPB). While an oxygenator change-out procedure may still be considered the gold standard for a confirmed device failure, temporizing measures exist that, in select cases, can afford time to the clinical team and even obviate the need for an oxygenator change-out procedure. We now consider the venous piggyback technique sourcing blood from the venous limb of the circuit a first-line intervention to afford enhanced patient safety while the clinical team decides on required interventions when oxygenator failure presents during CPB.

Indexed as

AlgorithmsCardiopulmonary BypassOxygenators, MembraneEquipment FailureExtracorporeal Membrane OxygenationHumansCardiopulmonary bypassCardiopulmonary bypass emergencyOxygenator change-outOxygenator failure

Identifiers

PMID39705587
PMCPMC11661781

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.