Evidence map›Paper›PMID 39705583›Full record

ReviewThe journal of extra-corporeal technology2024

Enhancing lung transplantation with ECMO: a comprehensive review of mechanisms, outcomes, and future considerations.

Salman Pervaiz Butt, Vivek Kakar, Salman Abdulaziz, Nabeel Razzaq, Yasir Saleem, Arun Kumar, Fazil Ashiq, Praveen Ghisulal, Aaron Thrush, Sadaf Malik and 11 more

Abstract readReview
In one paragraph

Review in The journal of extra-corporeal technology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Salman Pervaiz ButtInterim Manager Perfusion Services, Heart Vascular and Thoracic Institute, Cleveland Clinic, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Vivek KakarDirector ECMO Program, Critical Care Institute, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Salman AbdulazizConsultant of Cardiovascular Critical Care, Co-Chair of ECMO Task Force, Department of Health, United Arab Emirates.
Nabeel RazzaqClinical Perfusionist, Heart Vascular and Thoracic Institute, Cleveland Clinic, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Yasir SaleemPerfusionist, All India Institute of Medical Sciences, Sri Aurobindo Marg, Ansari Nagar, New Delhi 110029, India.
Arun KumarDepartment Chair, Cardiothoracic Aesthesia, Anesthesiology Institute, Cleveland Clinic, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Fazil AshiqAnesthesiology Physician, Anesthesiology Institute, Cleveland Clinic, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Praveen GhisulalCritical Care Associate Staff Physician, Critical Care Institute, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Aaron ThrushPhysical Therapist, Critical Care Institute, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Sadaf MalikPhysician Assistant, Critical Care Institute, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Mairead GriffinNurse Manager, Heart Vascular and Thoracic Institute, Cleveland Clinic, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Mahanoor AmirPhysical Therapist, Shalimar Medical and Dental College, Shalimar Link Road, Lahore, Punjab 54000, Pakistan.
Umar KhanCritical Care Consultant, Critical Care Institute, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Ashal SalimCharge Nurse, Critical Care Institute, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Zaid ZoumotDepartment Chair Pulmonology, Pulmonology Institute, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Izanee MydinConsultant Transplant Surgeon, The Newcastle Upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Freeman Road, High Heaton, NE7 7DN, UK.
Yazan AljaberyAssociate Staff Physician, Heart Vascular and Thoracic Institute, Cleveland Clinic, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Gopal BhatnagarInstitute Chair, Heart Vascular and Thoracic Institute, Cleveland Clinic, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Yusuf BayrakThoracic Physician, Heart Vascular and Thoracic Institute, Cleveland Clinic, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Andres ObesoThoracic Physician, Heart Vascular and Thoracic Institute, Cleveland Clinic, PO BOX 112412, Abu Dhabi, United Arab Emirates.
Usman AhmedDepartmental Chair Thoracic Surgery, Heart Vascular and Thoracic Institute, Cleveland Clinic, PO BOX 112412, Abu Dhabi, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung transplantation (LTx) is a critical intervention for patients with end-stage lung disease. However, challenges such as donor organ scarcity and post-transplant complications significantly affect its success. Recent advancements in Extracorporeal Membrane Oxygenation (ECMO) have shown promise in improving the outcomes and expanding eligibility for LTx.

methodsA comprehensive literature review was conducted, focusing on studies that explore the use of ECMO in lung transplantation. A thorough search of relevant studies on ECMO and LTx was conducted using multiple scholarly databases and relevant keywords, resulting in 73 studies that met the inclusion criteria. Sources included peer-reviewed journals and clinical trial results, with emphasis on articles captured recent advancements in ECMO technology and techniques.

resultsECMO has been crucial in supporting patients before, during, and after LTx. It serves as a bridge to transplantation by maintaining pulmonary and circulatory stability in critically ill patients awaiting donor organs. ECMO also aids in the evaluation of marginal donor lungs and supports patients through acute post-transplant complications. Recent technological advancements have improved the safety and efficacy of ECMO, further solidifying its role in LTx.

conclusionIn conclusion, this review underscores ECMO's critical role in enhancing outcomes across all stages of lung transplantation. Its various configurations and strategies have shown promise in stabilizing critically ill patients and improving transplant success rates. Looking ahead, it's important to gather more information about the long-term outcomes and potential complications associated with ECMO use. More research and data collection will help us understand the benefits and risks better, leading to improved decision-making and patient care in this field.

Indexed as

Extracorporeal Membrane OxygenationLung TransplantationHumansTreatment OutcomeCardiopulmonary bypass (CPB)ECMO (Extracorporeal Membrane Oxygenator)Lung transplantation (LTx)Primary graft dysfunction (PGD)

Identifiers

PMID39705583
PMCPMC11661783

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.