Evidence map›Paper›PMID 39705361›Full record

ReviewScience advances2024

Domain adaptation in small-scale and heterogeneous biological datasets.

Seyedmehdi Orouji, Martin C Liu, Tal Korem, Megan A K Peters

Abstract readReview
In one paragraph

Review in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Beyond the Classics: The Synergy of AI and Genomics Reveals an Expanded Repertoire of Pigmentation Genes.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2026
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  12. Toward the Best Generalizable Performance of Machine Learning in Modeling Omic and Clinical Data.Laboratory investigation; a journal of technical methods and pathology · 2025
    Article
  13. Article
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  16. How to develop good research questions.Nature human behaviour · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seyedmehdi OroujiDepartment of Cognitive Sciences, University of California Irvine, Irvine, CA, USA.ORCID 0000-0001-6293-8035
Martin C LiuDepartment of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0009-0002-3760-4249
Tal KoremProgram for Mathematical Genomics, Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0002-0609-0858
Megan A K PetersDepartment of Cognitive Sciences, University of California Irvine, Irvine, CA, USA.ORCID 0000-0002-0248-0816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Machine-learning models are key to modern biology, yet models trained on one dataset are often not generalizable to other datasets from different cohorts or laboratories due to both technical and biological differences. Domain adaptation, a type of transfer learning, alleviates this problem by aligning different datasets so that models can be applied across them. However, most state-of-the-art domain adaptation methods were designed for large-scale data such as images, whereas biological datasets are smaller and have more features, and these are also complex and heterogeneous. This Review discusses domain adaptation methods in the context of such biological data to inform biologists and guide future domain adaptation research. We describe the benefits and challenges of domain adaptation in biological research and critically explore some of its objectives, strengths, and weaknesses. We argue for the incorporation of domain adaptation techniques to the computational biologist's toolkit, with further development of customized approaches.

Indexed as

Computational BiologyMachine LearningDatabases, FactualHumans

Identifiers

PMID39705361
PMCPMC11661433

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.