Evidence map›Paper›PMID 39705295›Full record

ArticlePloS one2024

Dynamics of SARS-CoV-2 lineages in children and adults in 2021 and 2022.

Hiie Soeorg, Aare Abroi, Taavi Päll, Liidia Dotsenko, Erik Jaaniso, Katrin Kaarna, Andrio Lahesaare, Paul Naaber, Heiki Niglas, Ott Eric Oopkaup and 8 more

Abstract read
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In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Hiie SoeorgDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.ORCID 0000-0001-6475-7801
Aare AbroiFaculty of Science and Technology, Institute of Technology, University of Tartu, Tartu, Estonia.
Taavi PällDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Liidia DotsenkoDepartment of Communicable Diseases, Health Board, Tallinn, Estonia.
Erik JaanisoFaculty of Science and Technology, Institute of Computer Science, University of Tartu, Tartu, Estonia.
Katrin KaarnaClinical Research Centre, Faculty of Medicine, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
Andrio LahesaareSYNLAB Eesti OÜ, Tallinn, Estonia.
Paul NaaberDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Heiki NiglasDepartment of Communicable Diseases, Health Board, Tallinn, Estonia.
Ott Eric OopkaupHigh Performance Computing Center, Faculty of Science and Technology, Institute of Computer Science, University of Tartu, Tartu, Estonia.
Hedi PetersonFaculty of Science and Technology, Institute of Computer Science, University of Tartu, Tartu, Estonia.
Tuuli ReisbergFaculty of Science and Technology, Institute of Genomics, University of Tartu, Tartu, Estonia.ORCID 0000-0002-1193-5616
Olga SadikovaDepartment of Communicable Diseases, Health Board, Tallinn, Estonia.
Steven SmitFaculty of Science and Technology, Institute of Genomics, University of Tartu, Tartu, Estonia.ORCID 0000-0002-3791-635X
Ulvi Gerst TalasHigh Performance Computing Center, Faculty of Science and Technology, Institute of Computer Science, University of Tartu, Tartu, Estonia.ORCID 0000-0003-0485-089X
Radko AviDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Irja LutsarDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.ORCID 0000-0002-5082-429X
Kristi HuikDepartment of Microbiology, Faculty of Medicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to describe SARS-CoV-2 lineages and diversity in children and adults in Estonia and similarity to travel-related cases and neighbouring countries.

methodsSARS-CoV-2 sequences in 2021-2022 from a nationwide study were included. The proportion of predominant lineages in Estonian regions and among travel-related cases was described by multinomial logistic regression. Simpson's indices of diversity were compared using linear regression. Dynamics of Bray-Curtis dissimilarity was described by applying fuzzy clustering to non-metrical dimensional scaling results.

resultsA total of 2,630 sequences from children (<15 years) and 23,031 from adults (≥15 years) were included. The increase in the proportion of Alpha/Delta/Omicron BA.1/BA.2 lineages was delayed in smaller regions (by 3.5-27.5 days). The proportion of Alpha/Delta/Omicron BA.1 increased earlier among travel-related (n = 4,654) than non-travel-related cases (10.5 days). Diversity was lower in non-travel-related than travel-related cases until Delta period by 0.066. Dynamics of lineages and diversity were similar in adults and children. Similarity of lineages was delayed compared to Finland during Alpha/Omicron BA.1/BA.2 periods and different from all neighbouring countries during Delta period.

conclusionSARS-CoV-2 lineages in children and adults were similar. Differences between regions and travel-related cases and varying similarity to neighbouring countries suggest the importance of mobility in the spread.

Indexed as

COVID-19SARS-CoV-2AdolescentAdultChildChild, PreschoolEstoniaFemaleHumansMaleMiddle AgedPhylogenyTravelYoung Adult

Identifiers

PMID39705295
PMCPMC11661589

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.