Evidence map›Paper›PMID 39705073›Full record

ArticleThe Journal of cell biology2025

Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification.

Patricia M Kane

Abstract read
In one paragraph

Article in The Journal of cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Patricia M KaneDepartment of Biochemistry and Molecular Biology, State University of New York Upstate Medical University, Syracuse, NY, USA.ORCID 0000-0003-4210-1187

Funding

Regulation and Cellular Functions of V-ATPasesR35GM145256 · NIGMS · UPSTATE MEDICAL UNIVERSITY · PI PATRICIA M KANE · 2022 to 2026
$2.9M
NIGMS NIH HHS R35 GM145256NIH HHS R35 GM145256
6 · The paper itself

Abstract

Huda et al. (https://doi.org/10.1083/jcb.202406170) reveal a transient, cell cycle-dependent increase in PI(3,5)P2 levels at the lysosome-like vacuole of yeast daughter cells. The resulting lipid asymmetry alters vacuolar pH in both daughter and mother cells and will impact multiple downstream functions.

Indexed as

Phosphatidylinositol PhosphatesSaccharomyces cerevisiaeVacuolesCell CycleHydrogen-Ion ConcentrationLysosomesSaccharomyces cerevisiae Proteinsphosphatidylinositol 3,5-diphosphatePhosphatidylinositol PhosphatesSaccharomyces cerevisiae Proteins

Identifiers

PMID39705073
PMCPMC11661316

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.