Evidence map›Paper›PMID 39704968›Full record

ArticleDiscover oncology2024

The effect of stored autologous blood transfusion on IL-1, IL-6, TNF-α and liver function recovery in patients undergoing liver cancer surgery.

Dongliang Yin, Ruirong Niu, Peilin Lu, Ruilong Yin, Zhiqiang Lin

Abstract read
In one paragraph

Article in Discover oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dongliang YinDepartment of Hepatobiliary and Pancreatic Surgery, Dongguan People's Hospital, Dongguan, 523059, China. ydl1193@126.com.
Ruirong NiuDepartment of Neurosurgery, Dongguan People's Hospital, Dongguan, 523059, China.
Peilin LuDepartment of Hepatobiliary and Pancreatic Surgery, Dongguan People's Hospital, Dongguan, 523059, China.
Ruilong YinDepartment of Hepatobiliary and Pancreatic Surgery, Dongguan People's Hospital, Dongguan, 523059, China.
Zhiqiang LinDepartment of Hepatobiliary and Pancreatic Surgery, Dongguan People's Hospital, Dongguan, 523059, China.

Funding

The Social Science and Technology Development (General) Foundation of Donguan City 201950715001728
6 · The paper itself

Abstract

purposeThis study aim is to evaluate the application of stored autologous blood transfusion in liver cancer surgery and explore its impact on postoperative changes in inflammatory factors and liver function recovery.

methodThe study used a control group (CG) design and included 150 patients who underwent liver cancer surgery. While the observation group (OG) got autologous blood that had been preserved, the CG had a standard allogeneic blood transfusion. Examine the variations between the CG and the OG using the following measures: prior to, during, and following surgery contrast MELD score, blood routine indicators, pro-inflammatory cytokine levels.

resultMELD ratings, IL-1, IL-6, TNF-α levels, and preoperative blood routine indicators did not differ between the observation and CGs (p > 0.05). However, the blood routine indicators in the OG were lower than those in the CG on the first day following surgery (p < 0.05); seven days following surgery, there was no significant difference among the experiment participants (p > 0.05). In the meanwhile, the postoperative OG's levels of IL-1, IL-6, TNF-α, and HAF were lower than those of the CG (p < 0.05). The PVF of the OG was lower than the CG on the first day following surgery (p < 0.05), but on the seventh day following surgery, there was no discernible difference between the experiment's participants (p > 0.05).

conclusionThe research outcomes showcase that stored autologous blood transfusion can reduce the levels of inflammatory factors after surgery and promote the recovery of liver function;Research suggests important references for further understanding the application and mechanism of stored autologous blood transfusion, and provide a basis for personalized treatment and recovery of liver cancer patients undergoing surgery.

Indexed as

Liver cancer surgeryLiver functionPro-inflammatory cytokinesStored autologous blood transfusion

Identifiers

PMID39704968
PMCPMC11662106

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.