Evidence map›Paper›PMID 39704792›Full record

SynthesisDer Nervenarzt2025

[Long-term courses of anxiety disorders].

Jens Plag, Selina Heuer, Antonia Bendau, Andreas Ströhle

Abstract readReviewMeta-AnalysisEnglish Abstract
In one paragraph

Synthesis in Der Nervenarzt, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jens PlagInstitute for Mental Health and Behavioral Medicine, Fakultät für Medizin,, HMU Health and Medical University Potsdam, Olympischer Weg 1, 14471, Potsdam, Deutschland. jens.plag@hmu-potsdam.de.
Selina HeuerInstitute for Mental Health and Behavioral Medicine, Fakultät für Medizin,, HMU Health and Medical University Potsdam, Olympischer Weg 1, 14471, Potsdam, Deutschland.
Antonia BendauKlinik für Psychiatrie und Psychotherapie, CCM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Deutschland.
Andreas StröhleKlinik für Psychiatrie und Psychotherapie, CCM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAt present there is no comprehensive overview of the long-term development of the clinical picture, disease-associated impairments and neurobiological correlates of anxiety disorders as well as what influence certain risk factors and treatment have on the prognosis.

objectiveThis article presents findings regarding disorder-specific symptoms and disorder-associated changes in the areas of functional level, quality of life, neurocognitive performance and structural brain anatomy over the lifespan. It also reports on how patient-related and environment-related aspects as well as guideline-oriented therapy influence the course of the disorder. MATERIAL AND

methodsA literature search was conducted in PubMed on the aspects of individual components. Meta-analyses, longitudinal and cohort studies were included. To illustrate changes over time, the findings were predominantly presented separately for children and adolescents as well as for early and late adulthood.

resultsAnxiety disorders primarily exhibit age-associated differences in the symptom profile but also in the areas of functional level and quality of life. Risk factors for an unfavorable course of the disorder were identified particularly for young and middle-aged people; however, the findings indicate that evidence-based psychotherapy or pharmacotherapy also has a lasting effect even after termination.

conclusionFor long-term therapeutic success, age-dependent characteristics and limitations as well as prognostically relevant aspects in the diagnostics and treatment of anxiety disorders should be taken into consideration and treatment should be started as soon as possible.

Indexed as

Anxiety DisordersPsychotherapyQuality of LifeAdolescentAdultAgedChildFemaleHumansMaleMiddle AgedRisk FactorsTreatment OutcomeYoung AdultAge-associated differencessFunctional levelStructural imagingSymptomatologyTherapy

Identifiers

PMID39704792
PMCPMC11772529

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.