Evidence map›Paper›PMID 39704661›Full record

ArticleJournal of applied clinical medical physics2025

Partial and full arc with DynamicARC technique in pencil beam scanning proton therapy for bilateral head and neck cancer: A feasibility and dosimetric study.

Suresh Rana, Noufal Manthala Padannayil, Shyam Pokharel, Hina Saeed, Michael Kasper

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Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Suresh RanaDepartment of Radiation Oncology, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Boca Raton, Florida, USA.
Noufal Manthala PadannayilDepartment of Radiation Oncology, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Boca Raton, Florida, USA.
Shyam PokharelDepartment of Radiation Oncology, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Boca Raton, Florida, USA.
Hina SaeedDepartment of Radiation Oncology, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Boca Raton, Florida, USA.
Michael KasperDepartment of Radiation Oncology, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Boca Raton, Florida, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA novel proton beam delivery method known as DynamicARC spot scanning has been introduced. The current study aims to determine whether the partial proton arc technique, in conjunction with DynamicARC pencil beam scanning (PBS), can meet clinical acceptance criteria for bilateral head and neck cancer (HNC) and provide an alternative to full proton arc and traditional intensity-modulated proton therapy (IMPT).

methodThe study retrospectively included anonymized CT datasets from ten patients with bilateral HNC, all of whom had previously received photon treatment. The clinical target volumes (CTV) were categorized into three levels: CTV_7000, CTV_5950, and CTV_5600. IMPT plans included three beams, whereas DynamicARC plans included dual-partial-arcs (DPA), single-partial-arc (SPA), and single-full-arc (SFA). All plans underwent robust optimization considering setup (± 3 mm) and range (± 3%) uncertainties applied to the CTVs. DynamicARC plans were evaluated against the NRG-HN009 criteria and IMPT plans using various metrics.

resultsAll four techniques-IMPT, DPA, SPA, and SFA-demonstrated substantial compliance with NRG-HN009 dosimetric criteria. DynamicARC produced superior dose conformity, lower hotspot, and improved homogeneity for high-risk CTV compared to IMPT, with comparable performance for intermediate- and low-risk CTVs. DynamicARC reduced the D

conclusionOn the ProteusOne with a partial gantry system, DPA and SPA, in conjunction with DynamicARC PBS protons, provided clear dosimetric advantages over three-field IMPT. Future clinical implementation and further research into optimizing DynamicARC protocols are warranted to fully realize the benefits of these techniques in clinical settings.

Indexed as

Head and Neck NeoplasmsOrgans at RiskProton TherapyRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedFeasibility StudiesHumansRadiometryRadiotherapy DosageRetrospective StudiesDynamicARChead and neck cancerpencil beam scanningproton arcproton therapy

Identifiers

PMID39704661
PMCPMC11969107

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.