Evidence map›Paper›PMID 39704650›Full record

ArticleJournal of applied clinical medical physics2025

Hypoxia-guided treatment planning for lung cancer with dose painting by numbers.

Yazhou Li, Yuanyuan Ma, Jieyan Wu, Hui Zhang, Hongyi Cai, Xinguo Liu, Qiang Li

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yazhou LiInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Yuanyuan MaInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Jieyan WuGansu Provincial Hospital, Lanzhou, China.
Hui ZhangInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Hongyi CaiGansu Provincial Hospital, Lanzhou, China.
Xinguo LiuInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.
Qiang LiInstitute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.

Funding

Key Research and Development Program of Gansu Province 23YFFA0010National Key Research and Development Program of China 2022YFC2401503Top Leading Talents Project of Gansu Province 2023-9
6 · The paper itself

Abstract

Tumor hypoxia significantly impacts the efficacy of radiotherapy. Recent developments in the technique of dose painting by numbers (DPBN) promise to improve the tumor control probability (TCP) in conventional radiotherapy for hypoxic cancer. The study initially combined the DPBN method with hypoxia-guided dose distribution optimization to overcome hypoxia for lung cancers and evaluated the effectiveness and appropriateness for clinical use of the DPBN plans.

Indexed as

Lung NeoplasmsRadiotherapy, Image-GuidedRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedTumor HypoxiaFemaleHumansMaleOrgans at RiskPositron Emission Tomography Computed TomographyRadiotherapy DosageRetrospective Studiesdose painting by numbershypoxialung cancernormal tissue complication probabilitytumor control probability

Identifiers

PMID39704650
PMCPMC11969086

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.