Evidence map›Paper›PMID 39704532›Full record

ArticleAntimicrobial agents and chemotherapy2025

Bacteriophage treatment is effective against carbapenem-resistant

Panagiotis Zagaliotis, Jordyn Michalik-Provasek, Eleftheria Mavridou, Ethan Naing, Ioannis S Vizirianakis, Dimitrios Chatzidimitriou, Jason J Gill, Thomas J Walsh

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Phage therapy againstFrontiers in microbiology · 2026
    Review
  5. Article
  6. Bacteriophage treatment is effective against carbapenem-resistantAntimicrobial agents and chemotherapy · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Panagiotis ZagaliotisTransplantation/Oncology Program, Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0002-4669-957X
Jordyn Michalik-ProvasekDepartment of Microbial Pathogenesis and Immunology, Texas A&M University, College Station, Texas, USA.
Eleftheria MavridouTransplantation/Oncology Program, Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, USA.
Ethan NaingTransplantation/Oncology Program, Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, USA.
Ioannis S VizirianakisDepartment of Pharmacology, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Dimitrios ChatzidimitriouDeparment of Microbiology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Jason J GillDepartment of Animal Science, Texas A&M University Department of Animal Science, College Station, Texas, USA.ORCID 0000-0002-9494-6053
Thomas J WalshTransplantation/Oncology Program, Division of Infectious Diseases, Weill Cornell Medicine, New York, New York, USA.ORCID 0000-0002-7078-9778

Funding

Development of therapeutic bacteriophages against carbapenemase-resistant Klebsiella pneumoniaeR33AI121689 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI GILL, JASON J., WALSH, THOMAS · 2018 to 2020
$1.4M
Development of therapeutic bacteriophages against carbapenemase-resistant Klebsiella pneumoniaeR21AI121689 · NIAID · TEXAS A&M AGRILIFE RESEARCH · PI GILL, JASON J., WALSH, THOMAS · 2016 to 2017
$470k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 1R21/R33 AI121689-01NIAID NIH HHS R21 AI121689NIAID NIH HHS R33 AI121689
6 · The paper itself

Abstract

Carbapenemase-producing

Indexed as

BacteriophagesCarbapenem-Resistant EnterobacteriaceaeKlebsiella InfectionsKlebsiella pneumoniaeNeutropeniaPhage TherapyAnimalsAnti-Bacterial AgentsAzabicyclo CompoundsBacterial Translocationbeta-LactamasesCarbapenemsCeftazidimeDisease Models, AnimalDrug CombinationsFemaleAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo Compoundsbeta-LactamasesCarbapenemsCeftazidimeDrug Combinationsbacteriophagescarbapenem-resistant (KPC)gastrointestinal translocationKlebsiella pneumoniae (KPC)neutropenic murine modelrenal infection

Identifiers

PMID39704532
PMCPMC11823626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.