ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2025
The Fifth Annual Symposium of the Midwest Aging Consortium.
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Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- The Sixth Annual Symposium of the Midwest Aging Consortium.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
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Authors and funding
35 authors.
Brenda F ReaderDivision of Transplantation Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.ORCID 0000-0003-0418-2625
Lorena RosasDepartment of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.ORCID 0009-0005-9054-3045
Bailey Anna KnopfDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-7551-7248
Yang LiuDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Diego Alzate-CorreaDepartment of Biomedical Engineering, The Ohio State University, Columbus, Ohio, USA.
Ajay BhatDepartment of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0001-5021-0864
Anna CareyInstitute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0001-6735-6077
Ana Maria CuervoDepartment of Developmental and Molecular Biology, Institute for Aging Research, Albert Einstein College of Medicine, Bronx, New York, USA.
Sanjana DayalDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Rafael S DemarcoDepartment of Biology, University of Louisville, Louisville, Kentucky, USA.
Christian J ElliehausenDivision of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Davis A EnglundRobert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.
Haylee L HamiltonDivision of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Matthew JohnstonBiomedical Sciences Department, University of North Dakota, Grand Forks, North Dakota, USA.
Ping KangDepartment of Genetics, Development, and Cell Biology, Iowa State University, Ames, Iowa, USA.
Adam R KonopkaDivision of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0001-6655-6747
Noah LepolaDepartments of Molecular Genetics, Cancer Biology, and Genetics, The Ohio State University, Columbus, Ohio, USA.
Carolyn J PresleyDivision of Medical Oncology, Department of Medicine, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0002-2607-5639
Marissa J SchaferRobert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, Minnesota, USA.
Joan SerranoDepartment of Biological Chemistry and Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, USA.
Benjamin D SingerDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Min-Ae SongDivision of Environmental Health Sciences, College of Public Health, The Ohio State University, Columbus, Ohio, USA.
Kristin I StanfordDivision of General and Gastrointestinal Surgery, Department of Surgery, The Ohio State University College of Medicine, Columbus, Ohio, USA.
Jackson TaylorCenter for Gene Regulation in Health and Disease, Department of Biological, Geological, and Environmental Sciences, Cleveland State University, Cleveland, Ohio, USA.
Wei WeiDepartment of Pathology, Stanford University School of Medicine, Stanford, California, USA.
Chung-Yang YehDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Lei ZhangInstitute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0001-9798-0268
Lei ZhangInstitute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.ORCID 0000-0001-7409-6090
Rozalyn M AndersonGeriatric Research, Education, and Clinical Center, William S. Middleton Memorial Veterans Hospital, Madison, Wisconsin, USA.ORCID 0000-0002-0864-7998
Hua BaiDepartment of Genetics, Development, and Cell Biology, Iowa State University, Ames, Iowa, USA.ORCID 0000-0003-2221-7545
Paul D RobbinsInstitute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, USA.
Dudley W LammingDepartment of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-0079-4467
Maria M MihaylovaDepartment of Biological Chemistry and Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, USA.
Mauricio RojasDepartment of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.
Ana L MoraDepartment of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.
Funding
Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Daniel G. Stover · 1985 to 2026
$132.3MRole of Autophagy in T Cell Function and Immunosenescence (Project 3)P01AG031782 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI CUERVO, ANA MARIA · 2009 to 2024
$36.2MSomatic Activation of Retrotransposition: A New Molecular Mechanism of Aging?P01AG051449 · NIA · BROWN UNIVERSITY · PI John M Sedivy · 2016 to 2026
$30.4MTargeting Cellular Senescence to Extend HealthspanP01AG062413 · NIA · MAYO CLINIC ROCHESTER · PI Sundeep Khosla, Nathan K LeBrasseur · 2019 to 2026
$28.7MTissue resident macrophages regulate proteostasis in the aging lungP01AG049665 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI NAVDEEP S CHANDEL · 2015 to 2026
$26.9MTechnology CoreU19AI135964 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI RICHARD G WUNDERINK · 2018 to 2026
$24.7MValidation and characterization of the identified variants associated with human longevity in mouse modelsU19AG056278 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Zhengdong Zhang · 2017 to 2026
$24.5MThe Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6MProject 4: Comprehension of Health Risks in More and Less Arousing Affe p240-275P50CA180908 · NCI · OHIO STATE UNIVERSITY · PI SHIELDS, PETER G., WEWERS, MARY ELLEN · 2013 to 2017
$18.9MThe Cell Phenotyping and Mouse CoreP01HL154998 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KAREN M RIDGE · 2021 to 2026
$18.9MPROTEOMICSP01AG043376 · NIA · UNIVERSITY OF MINNESOTA · PI ROBBINS, PAUL D. · 2013 to 2019
$11.2MBiology of Aging and Age-Related Diseases Training GrantT32AG000213 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Rozalyn M. Anderson, Sanjay Asthana · 1991 to 2026
$9.9MAFAR/Hevolution New Investigator AwardAmerican Federation for Aging ResearchAmerican Heart Association AHA904048American Heart Association-American Stroke Association 24POST1196199American Heart Association Postdoctoral 1099 Fellowship 24POST1196199BLRD VA I01 BX001324BLRD VA IK6 BX006192Boehringer IngelheimCleveland State University startup fundsCollege of Public Health and James Comprehensive Cancer CenterCSRD VA I01 CX001932Department of Veterans Affairs Merit Review I01BX001324Food and Drug Administration Center for Tobacco Products P50CA180908Glen Foundation for Medical ResearchGlenn Foundation for Medical ResearchGlenn Foundation for Medical Research/AFARHevolution/AFARHevolution Award HF-GRO-23-1199062-14Hevolution Award AGE-003Hevolution Foundation PartnershipLisa Dean Moseley FoundationMcKnight Land-Grant ProfessorshipMedical Discovery Team on the Biology of Aging IK6BX006192National Institutes on Aging AG 060907NCATS NIH HHS UL1 TR001070NCI NIH HHS DP2 CA271361NCI NIH HHS P30 CA016058NCI NIH HHS P50 CA180908NCI NIH HHS R01 AG059711NCI NIH HHS UG3 CA275669NHLBI NIH HHS P01 HL154998NHLBI NIH HHS R01 HL147290NHLBI NIH HHS R01 HL147575NHLBI NIH HHS R01 HL149883NHLBI NIH HHS R01 HL153122NHLBI NIH HHS R01 HL168630NIAID NIH HHS R01 AI162778NIAID NIH HHS U19 AI135964NIAID NIH HHS U19 AI181102NIAMS NIH HHS K99 AR081898NIAMS NIH HHS R00 AR081898NIA NIH HHS F32 AG077916NIA NIH HHS K99 AG058798NIA NIH HHS K99 AG084921NIA NIH HHS P01 AG031782NIA NIH HHS P01 AG043376NIA NIH HHS P01 AG049665NIA NIH HHS P01 AG051449NIA NIH HHS P01 AG062413NIA NIH HHS R00 AG058798NIA NIH HHS R00 AG058800NIA NIH HHS R01 AG021961NIA NIH HHS R01 AG053832NIA NIH HHS R01 AG055529NIA NIH HHS R01 AG056771NIA NIH HHS R01 AG059711NIA NIH HHS R01 AG060542NIA NIH HHS R01 AG062328NIA NIH HHS R01 AG063543NIA NIH HHS R01 AG069819NIA NIH HHS R01 AG079913NIA NIH HHS R01 AG084156NIA NIH HHS R03 AG064374NIA NIH HHS R13 AG087673NIA NIH HHS R37 AG021904NIA NIH HHS R56 AG056771NIA NIH HHS R56 AG060907NIA NIH HHS RF1 AG056771NIA NIH HHS T32 AG000213NIA NIH HHS T32 AG049672NIA NIH HHS U01 AG081482NIA NIH HHS U19 AG056278NIBIB NIH HHS DP2 EB028110NIDDK NIH HHS DK125859NIDDK NIH HHS R01 DK098408NIDDK NIH HHS R01 DK125859NIDDK NIH HHS R01 DK133859NIGMS NIH HHS R35 GM134880NIGMS NIH HHS R35 GM140881NIH HHS 1DP2EB028110-01NIH HHS K99/R00 AG058798NIH HHS P01AG051449NIH HHS R00 AG058800NIH HHS R01 AG060542NIH HHS R01 AG063543-02S1NIH HHS R01 DK12744NIH HHS R01 HL149883NIH HHS R01 HL168630NIH HHS R03 AG064374NIH HHS R13AG087673NIH HHS R37 AG021904NIH HHS T32 AG000213NIH/NIA AG056771NINDS NIH HHS R01 NS132760Office of the NIH Director DP2CA271361OSU Davis Heart Lung Research InstituteOSU Division of Pulmonary, Critical Care, and Sleep MedicineOSU the Infectious Disease InstitutePelotonia Intramural Research FundsPew Charitable TrustsPrevent Cancer FoundationSan Antonio Nathan Shock Center Pilot GrantS. Parmar Travel AwardThe Ohio State UniversityThe Ohio State University Comprehensive Cancer CenterVAV Foundation
Abstract
As the healthcare burden caused by an increasingly aging population rapidly rises, a pressing need exists for innovative geroscience research that can elucidate aging mechanisms and precipitate the development of therapeutic interventions to support healthy aging. The Fifth Annual Midwest Aging Consortium Aging Research symposium, held from April 28 to 30, 2024, was hosted by The Ohio State University in Columbus, Ohio, and featured presentations from investigators across the Midwestern United States. This report summarizes the research presented at the symposium, whose topics included cellular senescence and the aging brain, metabolism and metabolic interventions, nutrition, redox mechanisms and biomarkers, and stress mechanisms. Abstract presentations and short talks highlighted early-stage and young investigators, whereas 2 keynote presentations anchored the symposium. Overall, this symposium showed the robustness of aging research in the Midwest and underscored the advantages of a collaborative approach to geroscience research.
Indexed as
AgingGeroscienceAgedCellular SenescenceCongresses as TopicHumansMidwestern United StatesBiomarkersCellular senescenceGeroscienceMetabolismNutritionStress
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