ArticleArtificial organs2025
Two Coupled Continuous-Flow Ventricular Assist Devices as a Novel BIVAD With One Driveline: Acute Animal Study Results.
Article in Artificial organs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Beyond Continuous-Flow: The Next Wave of Fully Implantable LVADs and Total Artificial Hearts.Current heart failure reports · 2026Review
- A Novel Biventricular Assist Device With a Single Driveline: A Report on the First Patient Treated.Artificial organs · 2026Article
- Implantation of a novel magnetically levitated biventricular assist device in a 10-year-old patient.JTCVS techniques · 2025Article
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe study assesses the feasibility of the DuoCor BiVAS, a novel biventricular assist system integrating magnetic levitation technology.
methodsIn an acute large animal model involving five sheep, each received the DuoCor BiVAS without cardiopulmonary bypass. Hemodynamic and device parameters were monitored continuously for 1-h post-implantation.
resultsIntraoperative implantation was uneventful, demonstrating successful biventricular support with mean blood flows of 5.4 LPM (left) and 5.5 LPM (right). Analysis showed proportional flow rates and relationships between pump speed, flow, and power consumption. No adverse events like thrombus formation, bleeding, stroke, or device failure occurred.
conclusionThis research underscores the DuoCor BiVAS's potential for severe biventricular heart failure treatment, providing insights into its feasibility and functionality in acute animal models. The findings suggest promising clinical applications, particularly with the system's single driveline design potentially enhancing patient mobilization and quality of life. Further investigations are needed to advance this technology for broader clinical use.
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