ArticleJournal of pediatric gastroenterology and nutrition2025
Prevalence and sequelae of asymptomatic Clostridioides difficile colonization in children with inflammatory bowel disease.
Article in Journal of pediatric gastroenterology and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Sub-inhibitory concentrations of metronidazole alter the proteomic profile and biological effects of extracellular vesicles from Clostridioides difficile.BMC microbiology · 2026Article
- The Gut Microbiome and Butyrate Differentiate Clostridioides difficile Colonization and Infection in Children.The Journal of infectious diseases · 2026Article
- Comparative genomic analysis ofMicrobial genomics · 2026Article
- Symptomatic from Clostridioides difficile or symptomatic from inflammatory bowel disease: Highlighting diagnostic challenges.Journal of pediatric gastroenterology and nutrition · 2025Article
- Prevalence and sequelae of asymptomatic Clostridioides difficile colonization in children with inflammatory bowel disease.Journal of pediatric gastroenterology and nutrition · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Colonization by Clostridioides difficile is common in children with inflammatory bowel disease (IBD) and complicates both the management of IBD and the diagnosis of C. difficile infection (CDI). There is a paucity of data on rates, risk factors, and outcomes associated with asymptomatic C. difficile colonization in children with IBD. We enrolled and prospectively followed 87 children with IBD without acute gastrointestinal symptoms. Twelve patients (13.8%) tested positive for C. difficile and were considered to have asymptomatic colonization. Elevated white blood cell count was associated with C. difficile colonization based on univariate regression. Three of the 12 (25%) C. difficile colonized patients were diagnosed with CDI in the 90 days following screening for C. difficile, versus 0 of the 75 who tested negative for C. difficile (p = 0.002). This data set the stage for further longitudinal tracking of children with IBD for C. difficile colonization and associated outcomes.
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Registered trials
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