Evidence map›Paper›PMID 39704091›Full record

ArticleEarly intervention in psychiatry2025

Self-Transcendence as a Risk and Resilience Factor in Individuals at Clinical High Risk for Psychosis.

Hollen N Reischer, Henry R Cowan, Kristen M Johnson, Vijay A Mittal

Abstract read
In one paragraph

Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hollen N ReischerDepartment of Psychology, University at Buffalo, State University of New York, Buffalo, New York, USA.ORCID 0000-0002-6538-0265
Henry R CowanDepartment of Psychology, Northwestern University, Evanston, Illinois, USA.ORCID 0000-0001-9891-6903
Kristen M JohnsonDepartment of Psychology, Northwestern University, Evanston, Illinois, USA.ORCID 0009-0008-3757-5795
Vijay A MittalDepartment of Psychology, Northwestern University, Evanston, Illinois, USA.ORCID 0000-0001-9017-5119

Funding

Prodromal Inventory for Negative Symptoms (PINS): A Development and Validation StudyR01MH116039 · NIMH · UNIVERSITY OF GEORGIA · PI MITTAL, VIJAY A, STRAUSS, GREGORY P · 2019 to 2023
$3.1M
2/5 CAPER Computerized assessment of psychosis riskR01MH120088 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2020 to 2024
$2.0M
High-Risk Psychosis Youth and Caregivers: Emotion in InteractionR21MH115231 · NIMH · NORTHWESTERN UNIVERSITY · PI HAASE, CLAUDIA, MITTAL, VIJAY A · 2017 to 2018
$484k
Using Speech Acoustics to Reveal Motor Disruptions in PsychosisR21MH119677 · NIMH · NORTHWESTERN UNIVERSITY · PI GOLDRICK, MATTHEW A, MITTAL, VIJAY A · 2019 to 2020
$424k
CIHR DFS-152268NIH HHS R01MH116039NIH HHS R01MH120088NIH HHS R21MH115231NIH HHS R21MH119677NIMH NIH HHS R01 MH116039NIMH NIH HHS R01 MH120088NIMH NIH HHS R21 MH115231NIMH NIH HHS R21 MH119677
6 · The paper itself

Abstract

aimSelf-transcendence is a personality feature and psychological resource that involves feelings of connectedness with the universe, all of humanity, and the individual self. Self-transcendence has been positively associated with both positive psychotic symptoms and clinical high risk for developing psychosis status, but studies reporting these findings focus solely on the connectedness-with-universe aspect of self-transcendence. The broader self-transcendence literature, which also includes connection with humanity and oneself, robustly supports self-transcendence as an indicator of well-being. Given this discrepancy, we sought to understand whether self-transcendence should be considered a risk or resilience factor for youth at clinical high risk.

methodsWe operationalised self-transcendence using two more holistic measures novel to the clinical high risk population. Clinical high risk participants (n = 42) and healthy controls (n = 44) completed the Adult Self-Transcendence Inventory and participated in narrative life story interviews which were coded for self-transcendence themes. RESULTS AND DISCUSSION: Clinical high risk individuals scored lower than healthy controls on measures of self-transcendence, functioning, and life satisfaction. However, there were no group differences in the relationships between self-transcendence and measures of well-being.

conclusionOur findings suggest self-transcendence is a part of healthy personality development that may be impacted in clinical high risk individuals yet may still function as a psychological resource for this population, pointing toward new avenues for intervention in clinical high risk and other mental health populations.

Indexed as

PersonalityPsychotic DisordersResilience, PsychologicalSelf ConceptAdolescentAdultCase-Control StudiesFemaleHumansMaleRisk FactorsYoung Adultadolescent well‐beingpersonal narratives as topicpsychological recoverypsychotic disordersresilience

Identifiers

PMID39704091
PMCPMC11729691

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.