ArticleFrontiers in aging neuroscience2024
ISLAND Campus: a fee-free formal university educational intervention in mid- to later-life to reduce modifiable risk factors for dementia and improve cognition.
Article in Frontiers in aging neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Hearing Loss and Modifiable Dementia Risk Factors in Adults Aged 50 Years or Older Living in Tasmania, Australia.Australasian journal on ageing · 2026Article
- Health-related factors and their impact on blood-based biomarkers of Alzheimer's disease.Aging brain · 2026Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Previous research has tended to focus on early-life education for dementia risk reduction, yet there are great gains for building cognitive reserve in mid- to later-life through educational interventions. ISLAND (Island Study Linking Ageing and Neurodegenerative Disease) Campus offered free university study to all ISLAND participants, with flexible in-person/online learning models to remove educational, socioeconomic and geographical barriers. Here the core hypothesis of ISLAND Campus was investigated: that engagement in later life education leads to improvements in modifiable risk factors for dementia, cognition and blood-based biomarkers. Methods: ISLAND Campus participants were matched on age and gender to non-Campus participants via propensity score method, with optimal matching based on logistic regression. Participants completed online surveys on health, demographics, modifiable dementia risk factors via a customized Dementia Risk Profile (DRP) tool and provided blood samples for APOE genotyping and plasma phosphorylated-tau (p-tau). Cognition was measured online via the validated Cambridge Neuropsychological Test Automated Battery Paired Associates Learning (PAL) and Spatial Working Memory (SWM) tasks. Impact of the opt-in formal educational intervention was tested in R via ANCOVA. Results: Total participants were 986 (interventio Discussion: ISLAND Campus has shown how free later-life university education was associated with improvements in modifiable dementia risk factors over time and cognition. Given opt-in intervention participants were significantly more likely to have a prior university education, later life formal educational interventions should be targeted at individuals with lower prior education.
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