ArticleJournal of nutritional science2024
A diet-wide association study for liver cancer risk: findings from a prospective cohort study in Chinese women.
Jia-Yi Tuo, Qiu-Ming Shen, Zhuo-Ying Li, Jing-Yu Tan, Yu-Ting Tan, Hong-Lan Li, Yong-Bing Xiang
Abstract read
In one paragraphArticle in Journal of nutritional science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
7 authors.
Jia-Yi TuoState Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Qiu-Ming ShenState Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhuo-Ying LiState Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jing-Yu TanState Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yu-Ting TanState Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hong-Lan LiState Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yong-Bing XiangState Key Laboratory of Systems Medicine for Cancer, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0002-3840-9915 Funding
Shanghai Womens Health StudyUM1CA182910 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ZHENG, WEI · 2014 to 2018
$5.9MNCI NIH HHS UM1 CA182910
6 · The paper itselfAbstract
Although dietary factors have been examined as potential risk factors for liver cancer, the evidence is still inconclusive. Using a diet-wide association analysis, our research evaluated the associations of 126 foods and nutrients on the risk of liver cancer in a Chinese population. We obtained the diet consumption of 72,680 women in the Shanghai Women's Health Study using baseline dietary questionnaires. The association between each food and nutrient and liver cancer risk was quantified by Cox regression model. A false discovery rate of 0.05 was used to determine the foods and nutrients which need to be verified. Totally 256 incident liver cancer cases were identified in 1,267,391 person-years during the follow-up duration. At the statistical significance level (
Indexed as
DietLiver NeoplasmsAdultAgedChinaDiet SurveysEast Asian PeopleFemaleFruitHumansMiddle AgedProportional Hazards ModelsProspective StudiesRisk FactorsSurveys and QuestionnairesVegetablesBMI, body mass indexCI, confidence intervalCohort studyDietDiet-wide association studyDWAS, Diet-wide association studyEPIC, European Prospective Investigation into Cancer and NutritionFDR, false discovery rateFFQ, food frequency questionnaireGWAS, genome-wide association studiesHBV, Hepatitis B virusHCC, hepatocellular carcinomaHCV, Hepatitis C virusHPFS, Health Professionals Follow-up StudyHR, hazard ratioIL-6, interleukin-6IQR, Inter quartile rangeLiver cancerMET, metabolic equivalentNHS, Nurses’ Health StudyNIH-AARP, National Institutes of Health-American Association of Retired Persons Diet and Health Study cohortNutritionPYs, person-yearsSWHS, Shanghai women’s health studyT2DM, type 2 diabetes mellitusWomen
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PMID39703897
PMCPMC11658938
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