Evidence map›Paper›PMID 39703737›Full record

ArticleRSC advances2024

Desorption of pharmaceutical hydrochlorides from transition metal oxide nanoparticles - investigation by capillary electrophoresis.

Eman T Elmorsi, Edward P C Lai

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eman T ElmorsiOttawa-Carleton Chemistry Institute, Department of Chemistry, Carleton University Ottawa ON K1S 5B6 Canada edward.lai@carleton.ca +1 (613) 520 3749 +1 (613) 520 2600 ext. 3835.
Edward P C LaiOttawa-Carleton Chemistry Institute, Department of Chemistry, Carleton University Ottawa ON K1S 5B6 Canada edward.lai@carleton.ca +1 (613) 520 3749 +1 (613) 520 2600 ext. 3835.ORCID https://orcid.org/0000-0002-6046-1138

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The binding affinity of pharmaceutical hydrochlorides onto transition metal oxide nanoparticles (TMONPs) was investigated through a consecutive process of adsorption and desorption. Mexiletine (MEX) was chosen as a model pharmaceutical hydrochloride that bound onto TMONPs' surface through electrostatic interactions and coordination bonding. Response surface methodology was applied for their optimal separation by capillary electrophoresis to achieve accurate quantitation. Linear and quadratic regressions were applied to model peak resolution and migration times. The response surface methodology was next applied to investigate the maximum desorption percentages of mexiletine (MEX) from the surface of TiO

Identifiers

PMID39703737
PMCPMC11656192

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.