Evidence map›Paper›PMID 39703391›Full record

ArticleFrontiers in pharmacology2024

A functional unbalance of TRPM8 and Kv1 channels underlies orofacial cold allodynia induced by peripheral nerve damage.

Ricardo Piña, Gonzalo Ugarte, Camilo Guevara, Richard Pino, Katherine Valdebenito, Sofía Romero, Ana Gómez Del Campo, Víctor Hugo Cornejo, María Pertusa, Rodolfo Madrid

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ricardo PiñaDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Gonzalo UgarteDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Camilo GuevaraDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Richard PinoDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Katherine ValdebenitoDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Sofía RomeroDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Ana Gómez Del CampoDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Víctor Hugo CornejoMillennium Nucleus for the Study of Pain - MiNuSPain, Santiago, Chile.
María PertusaDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.
Rodolfo MadridDepartamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Santiago, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cold allodynia is a debilitating symptom of orofacial neuropathic pain resulting from trigeminal nerve damage. The molecular and neural bases of this sensory alteration are still poorly understood. Here, using chronic constriction injury (CCI) of the infraorbital nerve (IoN) (IoN-CCI) in mice, combined with behavioral analysis, Ca

Indexed as

4-APAAV vectorsIKDinfraorbital nervePBMCprimary sensory neuronsthermotransduction

Identifiers

PMID39703391
PMCPMC11655194

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.