Evidence map›Paper›PMID 39703298›Full record

ArticleCureus2024

Recurrent Hypophosphatemia Following a Single Dose of Parenteral Iron Administration.

Swaroopa Kinnera, Oluwaseyi Owasoyo, Hafiz Muhammad Zahid Rahim, Asma Rahim, Kashish Keswani Sunil, Prabhav Chaudhary, Uzma Rahim, Abrar A Awan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Swaroopa KinneraAcute Medicine, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Oluwaseyi OwasoyoAcute Medicine, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Hafiz Muhammad Zahid RahimAcute Medicine, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Asma RahimAcute Medicine, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Kashish Keswani SunilAcute Medicine, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Prabhav ChaudharyAcute Medicine, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Uzma RahimAcute Medicine, Royal Stoke University Hospital, Stoke-on-Trent, GBR.
Abrar A AwanAcute Medicine, Royal Stoke University Hospital, Stoke-on-Trent, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although parenteral iron is widely used to treat iron deficiency anemia (IDA), some side effects have been inadequately explored. Hypophosphatemia is becoming a well-documented, yet poorly understood, side effect of parenteral iron infusion, oftentimes causing serious and/or prolonged complications. In this article, we discuss the case of a 33-year-old female with IDA who suffered debilitating physical and mental symptoms of significant recurrent hypophosphatemia following a single standard dose of parenteral iron administration. Despite initial management with repeated parenteral and oral phosphate replacement, the hypophosphatemia, along with its symptoms and sequelae, persisted until active vitamin D supplementation with calcitriol was commenced following a multispecialty team decision. This case highlights the deficiencies in the recognition and management of parenteral iron-induced hypophosphatemia and proposes a requirement for standardization in its management strategies, including the use of vitamin D supplementation.

Indexed as

calcitriolferric carboxymaltosefibroblast growth factor 23iron deficiency anaemiairon induced hypophosphataemiamechanism of phosphate regulationphosphatonins

Identifiers

PMID39703298
PMCPMC11656189

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.