Evidence map›Paper›PMID 39703252›Full record

ArticleCureus2024

Serotonin Syndrome in Parkinson's Disease: Don't Get It Confused by a Tremor.

José Diogo Martins, Rita Morais Passos, Nuno Pardal, Ana Catarina Carvoeiro, Fernando Correia

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

José Diogo MartinsInternal Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, PRT.
Rita Morais PassosCritical Care Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, PRT.
Nuno PardalInternal Medicine, Unidade Local de Saúde do Alto Minho, Viana do Castelo, PRT.
Ana Catarina CarvoeiroInternal Medicine, Unidade Local de Saude do Alto Minho, Viana do Castelo, PRT.
Fernando CorreiaIntermediate Care Unit, Unidade Local de Saúde do Alto Minho, Viana do Castelo, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serotonin syndrome (SS) is a potentially life-threatening condition caused by excessive serotonergic activity, often due to drug interactions. It classically manifests with autonomic and neuromuscular hyperactivity and by mental status changes that might include restlessness, delirium, and agitation. We present a case of a 76-year-old patient with Parkinson's disease with SS triggered by interaction between rasagiline and buspirone. He presented with altered mental status, hyperreflexia, and muscle rigidity. Due to the severity of symptoms, he was early admitted to the ICU, and his clinical condition improved after discontinuation of serotonergic agents and supportive care. In SS, a high index of suspicion is fundamental, so early treatment is implemented.

Indexed as

geriatric pharmacologyintensive care unit (icu)monoamine oxidase inhibitorsserotonergic toxicityserotonin syndrome (ss)

Identifiers

PMID39703252
PMCPMC11657359

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.