Evidence map›Paper›PMID 39703232›Full record

ArticlePNAS nexus2024

Insights into the regulation of CHIP E3 ligase-mediated ubiquitination of neuronal protein BNIP-H.

Srihari Shankar, Yaochen Liu, Nikhil Kumar Tulsian, Boon C Low, Qingsong Lin, J Sivaraman

Abstract read
In one paragraph

Article in PNAS nexus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Srihari ShankarDepartment of Biological Sciences, National University of Singapore, Singapore  117543.ORCID https://orcid.org/0000-0003-2540-969X
Yaochen LiuDepartment of Biological Sciences, National University of Singapore, Singapore  117543.
Nikhil Kumar TulsianDepartment of Biological Sciences, National University of Singapore, Singapore  117543.ORCID https://orcid.org/0000-0001-6577-6748
Boon C LowDepartment of Biological Sciences, National University of Singapore, Singapore  117543.ORCID https://orcid.org/0000-0003-0756-096X
Qingsong LinDepartment of Biological Sciences, National University of Singapore, Singapore  117543.
J SivaramanDepartment of Biological Sciences, National University of Singapore, Singapore  117543.ORCID https://orcid.org/0000-0001-9781-5326

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BCL2/adenovirus E1B 19-kDa protein-interacting protein 2 homolog (BNIP-H or Caytaxin), a pivotal adaptor protein that facilitates cerebellar cortex growth and synaptic transmission, is posttranslationally modified to regulate neuronal function. This study reports the ubiquitination of BNIP-H by Carboxyl terminus of Hsc70-Interacting Protein (CHIP), a U-box containing E3 ligase that is also regulated

Indexed as

BCH-domainE3 ligaseHDX-MSneuronubiquitination

Identifiers

PMID39703232
PMCPMC11658413

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.