Evidence map›Paper›PMID 39703017›Full record

ReviewSmall (Weinheim an der Bergstrasse, Germany)2026

Enhancing the Chemical Reactivity of Graphene through Substrate Engineering.

Jia Tu, Mingdi Yan

Abstract readReview
In one paragraph

Review in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Moiré-Induced Enhanced Hydrogen Adsorption on Graphene.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jia TuDepartment of Chemistry, University of Massachusetts Lowell, Lowell, MA, 01854, USA.
Mingdi YanDepartment of Chemistry, University of Massachusetts Lowell, Lowell, MA, 01854, USA.ORCID https://orcid.org/0000-0003-1121-4007

Funding

Division of Chemistry CHE-2305006
6 · The paper itself

Abstract

Covalent functionalization of pristine graphene can modify its properties, enabling applications in optoelectronics, biomedical fields, environmental science, and energy. However, the chemical reactivity of pristine graphene is relatively low, and as such, methods have been developed to increase the reactivity of graphene. This review focuses on substrate engineering as an effective strategy to enhance the reactivity of graphene through strain and charge doping. Nanoparticles, metals with different crystal orientations, and stretchable polymers are employed to introduce strains in graphene, leading to enhanced chemical reactivity and increased degree of functionalization. Charge doping through orbital hybridization with metals and charge puddles induced by oxide substrates generally enhance the reactivity of graphene, while alkyl-modified surfaces and 2D materials often reduce graphene reactivity via charge screening and van der Waals interactions that increase the stability of the graphene layer, respectively. This review summarizes methods for creating and characterizing strains and charge doping in graphene and discusses their effects on the chemical functionalization of graphene in various reactions.

Indexed as

charge dopinggraphene functionalizationstrainsubstrate engineering

Identifiers

PMID39703017
PMCPMC13137243

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.