Evidence map›Paper›PMID 39702997›Full record

ArticleEnvironmental microbiology2024

A CoA-Transferase and Acyl-CoA Dehydrogenase Convert 2-(Carboxymethyl)cyclohexane-1-Carboxyl-CoA During Anaerobic Naphthalene Degradation.

Yachao Kong, Jan Riebe, Malte Feßner, Torsten Schaller, Christoph Wölper, Florian Stappert, Sven W Meckelmann, Matthias Krajnc, Philip Weyrauch, Oliver J Schmitz and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Anaerobic degradation of polycyclic aromatic hydrocarbons.Applied and environmental microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yachao KongKey Laboratory of Coastal Biology and Bioresource Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, China.ORCID https://orcid.org/0009-0002-0207-4989
Jan RiebeOrganic Chemistry, Faculty of Chemistry and Center for Nanointegration, Duisburg-Essen (CENIDE), University of Duisburg-Essen, Essen, Germany.ORCID https://orcid.org/0000-0002-5555-5252
Malte FeßnerOrganic Chemistry II, Faculty of Chemistry and Biochemistry, Ruhr Universität Bochum, Bochum, Germany.
Torsten SchallerOrganic Chemistry, Faculty of Chemistry, University of Duisburg-Essen, Essen, Germany.
Christoph WölperInorganic Chemistry, Faculty of Chemistry, University of Duisburg-Essen, Essen, Germany.
Florian StappertApplied Analytical Chemistry, University of Duisburg-Essen, Essen, Germany.
Sven W MeckelmannApplied Analytical Chemistry, University of Duisburg-Essen, Essen, Germany.
Matthias KrajncOrganic Chemistry, Faculty of Chemistry and Center for Nanointegration, Duisburg-Essen (CENIDE), University of Duisburg-Essen, Essen, Germany.
Philip WeyrauchInstitute for Environmental Microbiology and Biotechnology, Aquatic Microbiology, University of Duisburg-Essen, Essen, Germany.
Oliver J SchmitzApplied Analytical Chemistry, University of Duisburg-Essen, Essen, Germany.
Christian MertenOrganic Chemistry II, Faculty of Chemistry and Biochemistry, Ruhr Universität Bochum, Bochum, Germany.
Jochen NiemeyerOrganic Chemistry, Faculty of Chemistry and Center for Nanointegration, Duisburg-Essen (CENIDE), University of Duisburg-Essen, Essen, Germany.
Xiaoke HuKey Laboratory of Coastal Biology and Bioresource Utilization, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai, China.
Rainer U MeckenstockInstitute for Environmental Microbiology and Biotechnology, Aquatic Microbiology, University of Duisburg-Essen, Essen, Germany.

Funding

Alexander von Humboldt-StiftungChina Scholarship Council 202004910604Deutsche Forschungsgemeinschaft NI1273/2-2Deutsche Forschungsgemeinschaft NI1273/4-1EXC-2033 390677874Internal Resources of University of Duisburg-EssenME 4267/5-1 418661145National Natural Science Foundation of China 32070112Taishan Scholar Project of Shandong Province of China Tspd20210317
6 · The paper itself

Abstract

The CoA thioester of 2-(carboxymethyl)cyclohexane-1-carboxylic acid has been identified as a metabolite in anaerobic naphthalene degradation by the sulfate-reducing culture N47. This study identified and characterised two acyl-CoA dehydrogenases (ThnO/ThnT) and an intramolecular CoA-transferase (ThnP) encoded within the substrate-induced thn operon, which contains genes for anaerobic degradation of naphthalene. ThnP is a CoA transferase belonging to the family I (Cat 1 subgroup) that catalyses the intramolecular CoA transfer from the carboxyl group of 2-(carboxymethyl)cyclohexane-1-carboxyl-CoA to its carboxymethyl moiety, forming 2-carboxycyclohexylacetyl-CoA. Neither acetyl-CoA nor succinyl-CoA functions as an exogenous CoA donor for this reaction. The flavin-dependent homotetrameric dehydrogenase ThnO is specific for (1R,2R)-2-carboxycyclohexylacetyl-CoA with an apparent K

Indexed as

Biodegradation, EnvironmentalCoenzyme A-TransferasesNaphthalenesAcyl-CoA DehydrogenaseAnaerobiosisBacterial ProteinsOperonAcyl-CoA DehydrogenaseBacterial ProteinsCoenzyme A-TransferasesnaphthaleneNaphthalenes

Identifiers

PMID39702997
PMCPMC11659651

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.