Evidence map›Paper›PMID 39702845›Full record

ArticleObesity surgery2025

Effect of Limb Length on Weight Loss Outcomes Following Biliopancreatic Diversion with Duodenal Switch: A Multi-Centered Study.

Marita Salame, Andre F Teixeira, Romulo Lind, Kamal Abi Mosleh, Muhammad Ghanem, Muhammad A Jawad, Michael L Kendrick, Omar M Ghanem

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marita SalameDepartment of Surgery, Mayo Clinic, Rochester, MN, 55905, USA.
Andre F TeixeiraDepartment of Surgery, Orlando Health, Orlando, FL, 32806, USA.
Romulo LindDepartment of Surgery, Orlando Health, Orlando, FL, 32806, USA.
Kamal Abi MoslehDepartment of Surgery, Mayo Clinic, Rochester, MN, 55905, USA.
Muhammad GhanemDepartment of Surgery, Orlando Health, Orlando, FL, 32806, USA.
Muhammad A JawadDepartment of Surgery, Orlando Health, Orlando, FL, 32806, USA.
Michael L KendrickDepartment of Surgery, Mayo Clinic, Rochester, MN, 55905, USA.
Omar M GhanemDepartment of Surgery, Mayo Clinic, Rochester, MN, 55905, USA. ghanem.omar@mayo.edu.ORCID 0000-0003-2459-2621

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe effectiveness of biliopancreatic diversion with duodenal switch (BPD/DS) for weight loss is well established, yet there remains ongoing debate over optimal limb lengths to maximize weight loss without compromising safety. We aimed to evaluate the impact of BPD/DS limb lengths on weight loss outcomes and comorbidity resolution. MATERIAL AND

methodsA multicenter review of patients who underwent primary BPD/DS between 2008 and 2022. Patient demographics, common channel (CC) length, Roux limb (RL) length, and weight loss outcomes at 6, 12, and 24 months were collected. Postoperative complications and comorbidity resolution were reported.

resultsA total of 720 patients (60 with 100-cm CC/150-cm RL length, 596 with 125-cm CC/125-cm RL length, 64 with 150-cm CC/150-cm RL length) were included with a mean follow-up of 21 ± 19 months. The %TWL at 24 months was higher in the 100/150 (44.1 ± 10.3%) and 125/125 (40.6 ± 10.6%) groups compared to the 150/150 group (35.9 ± 10.8%) (p < 0.001). After adjusting for age, preoperative BMI, gender, and diabetes status, CC length was independently associated with %TWL, showing a 1.8% decrease at 24 months for every 10-cm increase in CC length (p < 0.001). The 100/150 group had higher remission rates for T2DM (p = 0.007), OSA (p < 0.001), and HTN (p = 0.036) but also higher late complications (28.5% vs. 12.5%, 7%, p < 0.001). No significant early complications were observed (p = 0.149).

conclusionA shorter CC length of 100 cm is associated with greater weight loss and comorbidity resolution in BPD/DS patients up to 2 years after the surgery. Careful consideration of long-term risks is needed to minimize a higher prevalence of late complications. Further studies are necessary for sustained long-term weight loss outcomes.

Indexed as

Biliopancreatic DiversionDuodenumObesity, MorbidWeight LossAdultFemaleHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesTreatment OutcomeBiliopancreatic diversion with duodenal switchCommon channelWeight loss

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.