Evidence map›Paper›PMID 39702818›Full record

ArticleCommunications biology2024

Protogenin facilitates trunk-to-tail HOX code transition via modulating GDF11/SMAD2 signaling in mammalian embryos.

Yu-Sheng Hung, Wei-Mi Lin, Yu-Chiuan Wang, Wei-Chih Kuo, Yu-Yang Chen, Ming-Ji Fann, Jenn-Yah Yu, Yu-Hui Wong

Abstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu-Sheng HungDepartment of Life Sciences and Institute of Genome Sciences, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Wei-Mi Lin *Department of Life Sciences and Institute of Genome Sciences, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Yu-Chiuan Wang *Institute of Neuroscience, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Wei-Chih Kuo *Department of Life Sciences and Institute of Genome Sciences, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Yu-Yang ChenBrain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Ming-Ji FannDepartment of Life Sciences and Institute of Genome Sciences, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC).
Jenn-Yah YuDepartment of Life Sciences and Institute of Genome Sciences, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC). jyyu@nycu.edu.tw.ORCID 0000-0002-4006-3458
Yu-Hui WongDepartment of Life Sciences and Institute of Genome Sciences, College of Life Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan (ROC). yuhui.wong@nycu.edu.tw.ORCID 0000-0001-6941-6440

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During embryogenesis, vertebral axial patterning is intricately regulated by multiple signaling networks. This study elucidates the role of protogenin (Prtg), an immunoglobulin superfamily member, in vertebral patterning control. Prtg knockout (Prtg

Indexed as

Bone Morphogenetic ProteinsGene Expression Regulation, DevelopmentalGrowth Differentiation FactorsMice, KnockoutSignal TransductionSmad2 ProteinAnimalsBody PatterningEmbryo, MammalianEmbryonic DevelopmentEpidermal Growth FactorHomeodomain ProteinsHumansMembrane GlycoproteinsMiceNeoplasm ProteinsBone Morphogenetic ProteinsEpidermal Growth FactorGdf11 protein, mouseGrowth Differentiation FactorsHomeodomain ProteinsMembrane GlycoproteinsNeoplasm ProteinsSmad2 ProteinSmad2 protein, mouseTdgf1 protein, mouse

Identifiers

PMID39702818
PMCPMC11659552

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.