Evidence map›Paper›PMID 39702811›Full record

ArticleJournal of mathematical biology2024

Duration of transients in outbreaks: when can infectiousness be estimated?

Adam Mielke, Lasse Engbo Christiansen

Abstract read
In one paragraph

Article in Journal of mathematical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adam MielkeDepartment of Applied Mathematics and Computer Science, Technical University of Denmark, Asmussens Allé, 303B, 2800 Kgs., Lyngby, Denmark. admi@dtu.dk.ORCID 0000-0001-8605-2167
Lasse Engbo ChristiansenStatens Serum Institut, Artillerivej 5, 2300, Copenhagen S, Denmark.ORCID 0000-0001-5019-1931

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigate sub-leading orders of the classic SEIR-model using contact matrices from modeling of the Omicron and Delta variants of COVID-19 in Denmark. The goal of this is to illustrate when the growth rate, and by extension the infection transmission potential (basic or initial reproduction number), can be estimated in a new outbreak, e.g. after introduction of a new variant of a virus. In particular, we look at the time scale on which this happens in a realistic outbreak to guide future data collection. We find that as long as susceptible depletion is a minor effect, the transients are gone within around 3 weeks corresponding to about 4-5 times the incubation time. We also argue that this result generalizes to other airborne diseases in a fully mixed population.

Indexed as

Basic Reproduction NumberCOVID-19Disease OutbreaksMathematical ConceptsSARS-CoV-2DenmarkEpidemiological ModelsHumansModels, BiologicalPandemicsTime Factors34E1092D30

Identifiers

PMID39702811
PMCPMC11659369

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.