ArticleNPJ biofilms and microbiomes2024
Diverse polysaccharide production and biofilm formation abilities of clinical Klebsiella pneumoniae.
Article in NPJ biofilms and microbiomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Article
- Associations of Biofilm Capacity with Antimicrobial Resistance and Virulence Genes inAntibiotics (Basel, Switzerland) · 2026Article
- Biofilm-Forming Capacity andAntibiotics (Basel, Switzerland) · 2026Article
- Characterization of Proline-Rich Antimicrobial Peptides with SbmA Transporter-Dependent and Independent Antimicrobial Activity towardACS infectious diseases · 2026Article
- DksA-Dependent Stringent Stress Response Drives Virulence and Gastrointestinal Persistence ofbioRxiv : the preprint server for biology · 2026Article
- Different Cell Wall Compositions of ESKAPE Isolates on Glass Surfaces Impact Adhesion Adaptability to Dynamic Shear Stress.Microorganisms · 2026Article
- Phage-antibiotic synergy restores β-lactam efficacy in MDR Klebsiella quasipneumoniae biofilms and suppresses resistance.Journal of biomedical science · 2026Article
- Plug-and-play evolution of the Klebsiella pneumoniae capsule locus enables serotype exchange across genetic backgrounds.PLoS biology · 2026Article
- The acquisition ofmBio · 2026Article
- Genomic dissection of the clonal background and global dissemination of hypervirulent Klebsiella pneumoniae CG23-KL57 lineage.Nature communications · 2026Article
- Intestinal mucus acts as a nutrient source and signal forMicrobiome research reports · 2026Article
- Antibiofilm and Immunomodulatory Effects of Cinnamaldehyde in Corneal Epithelial Infection Models: Ocular Treatments Approach.Pharmaceutics · 2025Article
- Molecular response to the non-lytic peptide bac7 (1-35) triggers disruption of Klebsiella pneumoniae biofilm.PLoS pathogens · 2025Article
- The acquisition ofbioRxiv : the preprint server for biology · 2025Article
- UropathogenicMicroorganisms · 2025Article
- Phenotypic, transcriptomic and metabolomic changes in Klebsiella pneumoniae after long term exposure to simulated microgravity.NPJ microgravity · 2025Article
- Article
- Molecular epidemiology of carbapenem-resistantFrontiers in microbiology · 2025Article
- TheFrontiers in microbiology · 2025Article
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Abstract
Klebsiella pneumoniae infections have become a growing threat for human health. The lack of understanding of the relationship between antibiotic resistance, mucoviscosity, and biofilm formation impedes our abilities to effectively predict K. pneumoniae infection outcomes. The Multidrug-Resistant Organism Repository and Surveillance Network offers a unique opportunity into the genetic and phenotypic variabilities in the K. pneumoniae isolates. To this end, we compared the genetic profiles of these isolates with the phenotypic biofilm formation, percent mucoviscosity, and growth rates. There was a significant phenotype-genotype correlation with decreased biofilm formation and an insertion sequence in the transcriptional activator of the type III fimbrial system. Interestingly, the most mucoid strains in the populations were lacking the genetic element regulating the mucoid phenotype and three of these isolates were able to form robust biofilms. The combination of phenotypic, genomic, and image analyses revealed an intricate relation between growth, mucoviscosity and specific virulence-associated genetic determinants.
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