Evidence map›Paper›PMID 39702673›Full record

ArticleNPJ digital medicine2024

Mitigation of AI adoption bias through an improved autonomous AI system for diabetic retinal disease.

Michael D Abràmoff, Philip T Lavin, Julie R Jakubowski, Barbara A Blodi, Mia Keeys, Cara Joyce, James C Folk

Registry-linked trialAbstract read
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05808699 (Camera Qualification of an Additional Fundus Camera Paired With An Autonomous AI for Detecting Diabetic Retinopathy), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05808699 active not recruitingnot on this map

Camera Qualification of an Additional Fundus Camera Paired With An Autonomous AI for Detecting Diabetic Retinopathy

TypeobservationalSponsorDigital Diagnostics, Inc.Ran2023 to 2025Enrolled626ConditionsDiabetic RetinopathyArmshandheld fundus camera
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael D AbràmoffDepartment of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USA. michael-abramoff@uiowa.edu.
Philip T LavinBoston Biostatistics Research Foundation, Inc., Framingham, MA, USA.
Julie R JakubowskiBaxter International Inc, Deerfield, IL, USA.
Barbara A BlodiDepartment of Ophthalmology and Visual Sciences, Wisconsin Reading Center, University of Wisconsin, Madison, WI, USA.
Mia KeeysDepartment of Public Health, George Washington University, Washington, DC, USA.
Cara JoyceDepartment of Medicine, Stritch School of Medicine, Loyola University Chicago, Chicago, IL, USA.
James C FolkDepartment of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Where adopted, Autonomous artificial Intelligence (AI) for Diabetic Retinal Disease (DRD) resolves longstanding racial, ethnic, and socioeconomic disparities, but AI adoption bias persists. This preregistered trial determined sensitivity and specificity of a previously FDA authorized AI, improved to compensate for lower contrast and smaller imaged area of a widely adopted, lower cost, handheld fundus camera (RetinaVue700, Baxter Healthcare, Deerfield, IL) to identify DRD in participants with diabetes without known DRD, in primary care. In 626 participants (1252 eyes) 50.8% male, 45.7% Hispanic, 17.3% Black, DRD prevalence was 29.0%, all prespecified non-inferiority endpoints were met and no racial, ethnic or sex bias was identified, against a Wisconsin Reading Center level I prognostic standard using widefield stereoscopic photography and macular Optical Coherence Tomography. Results suggest this improved autonomous AI system can mitigate AI adoption bias, while preserving safety and efficacy, potentially contributing to rapid scaling of health access equity. ClinicalTrials.gov NCT05808699 (3/29/2023).

Identifiers

PMID39702673
PMCPMC11659561

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.