Evidence map›Paper›PMID 39702312›Full record

ReviewNature communications2024

The need for adaptability in detection, characterization, and attribution of biosecurity threats.

William Mo, Christopher A Vaiana, Chris J Myers

Abstract readReview
In one paragraph

Review in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

William MoDraper Scholar, The Charles Stark Draper Laboratory, Inc., 555 Technology Square, Cambridge, MA, USA.ORCID 0009-0000-6356-9219
Christopher A VaianaThe Charles Stark Draper Laboratory, Inc., 555 Technology Square, Cambridge, MA, USA.
Chris J MyersDepartment of Electrical, Computer, and Energy Engineering, University of Colorado Boulder, 1111 Engineering Dr, Boulder, CO, USA. chris.myers@colorado.edu.ORCID 0000-0002-8762-8444

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern biotechnology necessitates robust biosecurity protocols to address the risk of engineered biological threats. Current efforts focus on screening DNA and rejecting the synthesis of dangerous elements but face technical and logistical barriers. Screening should integrate into a broader strategy that addresses threats at multiple stages of development and deployment. The success of this approach hinges upon reliable detection, characterization, and attribution of engineered DNA. Recent advances notably aid the potential to both develop threats and analyze them. However, further work is needed to translate developments into biosecurity applications. This work reviews cutting-edge methods for DNA analysis and recommends avenues to improve biosecurity in an adaptable manner.

Indexed as

BioterrorismSecurity MeasuresBiotechnologyDNAHumansDNA

Identifiers

PMID39702312
PMCPMC11659417

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.