ArticleBMC musculoskeletal disorders2024
Global, regional and national burden of osteoarthritis in 1990-2021: a systematic analysis of the global burden of disease study 2021.
Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 3 of them syntheses that pooled it.
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Who cites it
39 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Implementation research on osteoarthritis in Asia: a systematic review.Frontiers in public health · 2026Pooled it
- Outcomes of cemented and hybrid primary total hip arthroplasty for osteoarthritis: A systematic review with narrative synthesis.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Effectiveness of AI-assisted rehabilitation for musculoskeletal disorders: a network meta-analysis of pain, range of motion, and functional outcomes.Frontiers in bioengineering and biotechnology · 2025Pooled it
- Telerehabilitation intervention after total knee arthroplasty in Iran: a feasibility and acceptability randomised controlled trial.BMJ open · 2026Trial
- Cultural practices and knee osteoarthritis in Central Asia: a case-control study on risk and protective factors.Future science OA · 2026Article
- Global burden of osteoarthritis attributable to high body mass index (1990-2021): rising trends with marked sex-age disparities and prediction to 2050.Clinical rheumatology · 2026Article
- Low-power infrared laser on telomere maintenance in an experimental model of arthritis.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Article
- A Contrastive Domain Adaptation Framework for Knee Osteoarthritis Severity Grading.Bioengineering (Basel, Switzerland) · 2026Article
- Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway.Molecular medicine reports · 2026Article
- Review
- Evolving Global Burden of GBD-Defined Spinal Cord Lesions, 2014-2023: A Global Burden of Disease Analysis of the Geriatric Transition and Anatomical Distribution.Journal of clinical medicine · 2026Article
- Risk factors for postoperative ecchymosis after medial open-wedge high tibial osteotomy: an exploratory analysis of thromboelastography parameters.BMC surgery · 2026Article
- Cryogel-based therapeutic platforms for disease modification in osteoarthritis.npj biomedical innovations · 2026Review
- Comparative Short-Term Clinical Outcomes of Hybrid Hyaluronic Acid and Platelet-Rich Plasma Injections in Knee Degenerative Conditions: An Exploratory Real-World Retrospective Study.Medicina (Kaunas, Lithuania) · 2026Article
- Smart Nanodelivery Systems for Immunometabolic Modulation in Osteoarthritis.Exploration (Beijing, China) · 2026Review
- Neuromuscular exercise combined with pain neuroscience education for knee osteoarthritis management in older women: protocol for a randomized controlled trial.Journal of orthopaedic surgery and research · 2026Article
- Sleep Quality and Sleep Health Before and After Hip or Knee Arthroplasty: A Prospective Cohort Study.Journal of clinical medicine · 2026Article
- Effects of a preoperative exercise intervention targeting the non-operated limb in patients scheduled for total knee arthroplasty: a pilot study.Journal of physical therapy science · 2026Article
- Perceptions regarding the use of cannabis in orthopaedics for treating musculoskeletal joint pain: A survey of arthritis patients.The Journal of international medical research · 2026Article
- Review
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectivesTo describe the prevalence and incidence of osteoarthritis as well as years lived with disability (YLDs) due to osteoarthritis in 204 countries and territories from 1990 to 2021 by age, sex and socio-demographic index (SDI, a composite of socio-demographic factors).
methodsData were acquired from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 (GBD 2021). The burden of osteoarthritis was estimated for 204 countries and territories from 1990 to 2021by incidence, prevalence and YLDs. All estimates are presented as numbers and age-standardised rates per 100 000 population, with uncertainty intervals (UIs). All the data were analyzed by age-sex-SDI-year groups.
resultsIn 2021, globally, the age-standardised prevalence rate of osteoarthritis increased from 6393.1(95% UI 5683.2 to 7059.5) in 1990 to 6967.3(95% UI 6180.7 to 7686.1) in 2021.Addtionally, the age-standardised incidence rate increased from 489.8(95% UI 541.5 to 433.1) in 1990 to 535.0(95% UI 472.4 to 592.0) in 2021. In addition, the age-standardised YLD rate of osteoarthritis increased from 222.8(95% UI 106.7 to 450.3) in 1990 to 244.5(95% UI 117.1 to 493.1). The global prevalence and YLDs were higher in females than in males and increased with age, peaking at the > 95 years age group. Simultaneously, a positive association was found between the age-standardised YLD rate and the SDI at the regional and national levels.
conclusionsOsteoarthritis is a major public health challenge that can cause significant problems for individuals and society. The burden osteoarthritis increased in most countries between 1990 and 2021. This trend is expected to continue as life expectancy increases and the global population ages. Increasing public awareness of the risk factors and the importance of osteoarthritis management, along with providing healthcare services to the growing number of people with osteoarthritis, are recommended to manage the future burden of this disease.
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