Evidence map›Paper›PMID 39702235›Full record

ArticleBMC musculoskeletal disorders2024

The effect of a low-carbohydrate diet on evoked pain and quality of life in Non-Hispanic black women with knee osteoarthritis: a pilot study.

Asia M Wiggins, Larissa J Strath, Gray E McPherson, Barbara A Gower, Amy M Goss, Burel R Goodin, Robert E Sorge

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04343716 (Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04343716 nacompletednot on this map

Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2020 to 2023Enrolled19ConditionsKnee OsteoarthritisArmsLow-carbohydrate diet
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Asia M WigginsDepartment of Psychology, University of Alabama at Birmingham, 1300 University Blvd, Birmingham, AL, 35233, United States.
Larissa J StrathCollege of Medicine, University of Florida, Gainesville, FL, United States.
Gray E McPhersonDepartment of Psychology, University of Alabama at Birmingham, 1300 University Blvd, Birmingham, AL, 35233, United States.
Barbara A GowerDepartment of Nutrition Sciences, School of Health Professions, University of Alabama at Birmingham, Birmingham, AL, United States.
Amy M GossDepartment of Nutrition Sciences, School of Health Professions, University of Alabama at Birmingham, Birmingham, AL, United States.
Burel R GoodinDepartment of Anesthesiology, School of Medicine, Washington University, St Louis, MO, United States.
Robert E SorgeDepartment of Psychology, University of Alabama at Birmingham, 1300 University Blvd, Birmingham, AL, 35233, United States. rsorge@uab.edu.

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
Research Education CoreP30AG031054 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CLAY, OLIVIO J · 2007 to 2025
$11.6M
NIA NIH HHS 3P30AG031054-14S1NIA NIH HHS P30 AG031054NIDDK NIH HHS P30 DK056336NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

backgroundKnee osteoarthritis (KOA) is a prevalent chronic pain condition that can significantly impact quality of life and contribute to recognized chronic pain racial disparities. We have shown that a low-carbohydrate diet (LCD) can reduce KOA-related pain. Our previous work suggested that the LCD was more beneficial for women and non-Hispanic Black (NHB) adults, but our sample was not sufficiently diverse. Thus, we sought to determine whether the LCD may be beneficial for NHB women with KOA on measures of self-reported and evoked pain.

methodsFourteen NHB women (M = 55.93, S.D. = 7.79 years of age) with KOA were recruited to participate in a pilot 6-week LCD intervention. Measures of pain sensitivity, disability, physical functioning, overall chronic pain, quality of life, and dietary habits were taken at baseline and at 3- and 6-weeks of the LCD intervention.

resultsOverall, participants showed significant differences in self-reported measures of daily pain, pain interference, stiffness, physical functioning, depressive symptoms, food knowledge and food security. Participants also showed reduced evoked pain in the timed walk and chair stand tasks.

conclusionA 6-week LCD provided a range of benefits related to pain and quality of life in NHB women with KOA. The utilization of a LCD is a modifiable, non-pharmacological and accessible alternative for chronic KOA that may reduce pain disparities and improve quality of life.

trial registrationThis article reports the original results of a dietary healthcare intervention registered at clinicaltrials.gov (NCT04343716, registered on 13/04/2020).

Indexed as

Black or African AmericanDiet, Carbohydrate-RestrictedOsteoarthritis, KneeQuality of LifeChronic PainFemaleHumansMiddle AgedPain MeasurementPilot ProjectsTreatment OutcomeChronic painKnee osteoarthritis (KOA)Low-carbohydrate diet (LCD)Non-hispanic Black (NHB)

Identifiers

PMID39702235
PMCPMC11660617

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.