ArticleBMC oral health2024
CGF with Bio-Oss collagen as grafting materials for simultaneous implant placement after osteotome sinus floor elevation: a prospective study.
Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- A study on the osteogenic effect of CGF membrane combined with bone graft in rabbit calvarial defects.BMC oral health · 2026Article
- Effect of implant protrusion length on intrasinus bone formation in transalveolar sinus lift without grafting: a meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- Multimodal analysis of biomineralization within a collagen scaffolding in a rat calvarial defect model by using decalcified and undecalcified specimens.Journal of materials science. Materials in medicine · 2026Article
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4 authors.
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Abstract
backgroundOsteotome sinus floor elevation (OSFE) procedure with simultaneous implant placement is known to be an efficient procedure in the atrophic maxilla, where bone regeneration is required the most. The purpose of this study was to radiologically evaluate the efficacy of using Bio-Oss Collagen with Concentrated Growth Factor (CGF) as grafting materials for OSFE with simultaneous implant placement in the atrophic maxilla after one year of functional loading.
methodsA total of 126 implants were placed for 123 patients. Our inclusion criteria were patients with Residual Bone Height (RBH) ≤ 5 whom underwent OSFE procedure and simultaneous implant placement with different grafting materials: Group A with no grafting materials, Group B with Bio-Oss bone graft, and Group C with Bio-Oss Collagen with CGF. The Implants Survival Rate (ISR) was the primary outcome variable. Secondary outcome variables included radiographic measurements assessed at four follow-up time points, the Implant Stability Quotient (ISQ), and bone density (B). Indicators of bone formation were compared at different time points. Appropriate statistical analyses were conducted, with statistical significance set at a P value of 0.05 for all tests.
resultsISR was 96%. A significant positive relationship was found between RBH and ISR, [r (126) = .359, p = .000]. Endo sinus bone gain indictors increased in both grafted groups as compared to the non-grafted group. Total Bone Resorption (TBR1) and (TBR2) significantly decreased in both grafted groups compared to the non-grafted group (P = .004, P = .000). Graft size (D) was a positive predictor for ISR at three time points: D0 (odds ratio [OR] 8.06; 95% CI 1.59 to 38.24; P = .010); D1 (OR 96.58; 95% CI 1.69 to 5.52; P = .027); D2 (OR 4.97; 95% CI 1.29 to 19.19; P = .020). Visual Analog Scale (VAS) pain score significantly increased in Group B compared to Groups A and C (P = .000).
conclusionThe combination of Bio-Oss Collagen with CGF as grafting material is a reliable protocol after OSFE with simultaneous implant placement in the atrophic maxilla. This approach is accompanied by high patient satisfaction.
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