Evidence map›Paper›PMID 39702204›Full record

ArticleBMC musculoskeletal disorders2024

Association between postoperative intravenous methylprednisolone and surgical site infection in posterior lumbar fusion surgery: a retrospective single-center study.

Yuancheng Zhang, Jiahua Xie, Tianzuo Niu, Siping Deng, Jianru Wang, Hui Liu, Zemin Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuancheng Zhang *Department of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jiahua Xie *Department of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Tianzuo NiuDepartment of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Siping DengDepartment of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jianru WangDepartment of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Hui LiuDepartment of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. liuhui58@mail.sysu.edu.cn.
Zemin LiDepartment of Spine Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. lizm25@mail.sysu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the association between intravenous methylprednisolone administration and the risk of surgical site infection (SSI) following posterior lumbar fusion (PLF) surgery.

methodsThis retrospective, single-center study analyzed data from 800 adult patients who underwent elective PLF surgery at our institution. Patients were classified according to postoperative intravenous methylprednisolone administration. Univariate and multivariable logistic regression, and subgroup analysis were used to assess the association between methylprednisolone administration and SSI risk, as well as its impact on postoperative pain management.

resultsOur analysis showed no significant association between intravenous methylprednisolone administration and the development of a SSI after PLF. Subgroup analyses suggested that methylprednisolone was potentially protective in patients with a body mass index (BMI) < 25 kg/m

conclusionsThis study suggests that intravenous methylprednisolone administration may not increase the risk of SSI after single-level PLF. In addition, it appears to have a beneficial effect on postoperative pain management and PONV, especially during the early recovery phase.

Indexed as

Administration, IntravenousLumbar VertebraeMethylprednisolonePostoperative PainSpinal FusionSurgical Wound InfectionAdultAgedFemaleHumansMaleMiddle AgedPostoperative Nausea and VomitingRetrospective StudiesMethylprednisoloneIntravenous methylprednisone administrationPain managementPosterior lumbar fusionSurgical site infection

Identifiers

PMID39702204
PMCPMC11660551

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.