Evidence map›Paper›PMID 39702188›Full record

Observational studyBMC oral health2024

Demographic and clinicopathological comparison among oral lichen planus, lichenoid lesions and proliferative verrucous leukoplakia: a retrospective study.

Milena Duarte Moreira, Fernanda Doyle Maia, Viviane Limongi Zimbrão, Emilly Collodetti, Tânia Regina Grão-Velloso, Liliana Aparecida Pimenta-Barros, Simone de Queiroz Chaves Lourenço, Danielle Resende Camisasca

Abstract readObservational StudyComparative Study
In one paragraph

Observational study in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Milena Duarte MoreiraDental Sciences Graduate Program. Federal University of Espirito Santo (UFES), Avenida Maruípe 1468, Maruípe, Vitória, 29040-090, ES, Brazil.
Fernanda Doyle MaiaDental Sciences Graduate Program. Federal University of Espirito Santo (UFES), Avenida Maruípe 1468, Maruípe, Vitória, 29040-090, ES, Brazil.
Viviane Limongi ZimbrãoDentistry Graduate Program. Federal Fluminense University (UFF), Niterói, RJ, Brazil.
Emilly CollodettiDental Sciences Graduate Program. Federal University of Espirito Santo (UFES), Avenida Maruípe 1468, Maruípe, Vitória, 29040-090, ES, Brazil.
Tânia Regina Grão-VellosoDental Sciences Graduate Program. Federal University of Espirito Santo (UFES), Avenida Maruípe 1468, Maruípe, Vitória, 29040-090, ES, Brazil.
Liliana Aparecida Pimenta-BarrosDental Sciences Graduate Program. Federal University of Espirito Santo (UFES), Avenida Maruípe 1468, Maruípe, Vitória, 29040-090, ES, Brazil.
Simone de Queiroz Chaves LourençoDentistry Graduate Program. Federal Fluminense University (UFF), Niterói, RJ, Brazil.
Danielle Resende CamisascaDental Sciences Graduate Program. Federal University of Espirito Santo (UFES), Avenida Maruípe 1468, Maruípe, Vitória, 29040-090, ES, Brazil. danielle.camisasca@ufes.br.

Funding

FAPES - Fundação de Amparo à Pesquisa e Inovação do Espírito Santo, Brazil 85283215 (Edital FAPES/CNPq PPP 22/2018)Fundação de Amparo à Pesquisa e Inovação do Espírito Santo 2022-G69LF
6 · The paper itself

Abstract

backgroundClinicopathological diagnosis and follow-up of oral lichen planus and leukoplakia are necessary due to its potential for malignant transformation and the need to differentiate it from other lichenoid diseases and proliferative verrucous leukoplakia. This study aimed to classify and compare sociodemographic and clinicopathological features among patients with oral lichen planus, oral lichenoid lesions and proliferative verrucous leukoplakia.

methodsA transversal observational study in which oral leukoplakia and oral lichen planus patients were surveyed at the Oral Pathological Anatomy Service and Applied Biotechnology Laboratory was conducted. Sociodemographic and clinicopathological data were compared for the lesions studied with the chi-square test or Fisher's exact test.

resultsAfter classification, 21 oral lichen planus lesions, 34 oral lichenoid lesions and 12 proliferative verrucous leukoplakia lesions were evaluated. Reticular patterns are more characteristic of oral lichen planus and plaque lesions of proliferative verrucous leukoplakia. The buccal mucosa was the most affected site in oral lichen planus lesions, and it was bilateral in all patients. Epithelial dysplasia was present in almost all patients with proliferative verrucous leukoplakia.

conclusionsCompared with oral lichen planus and proliferative verrucous leukoplakia, oral lichenoid lesions presented intermediate features. This may delay proliferative verrucous leukoplakia diagnosis.

Indexed as

Leukoplakia, OralLichenoid EruptionsLichen Planus, OralAdultAgedCross-Sectional StudiesDiagnosis, DifferentialFemaleHumansMaleMiddle AgedMouth MucosaRetrospective StudiesDiagnosis-related groupsDifferential diagnosisOral leukoplakiaOral lichen planusSquamous cell carcinoma

Identifiers

PMID39702188
PMCPMC11661046

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.